Jackson Ramon J, Chavarria Hector D, Hacking Sean M
Department of Pathology and Laboratory Medicine, Donald and Barbara Zucker School of Medicine, New York, USA.
Cureus. 2020 Sep 29;12(9):e10722. doi: 10.7759/cureus.10722.
The outbreak of the novel coronavirus (2019-nCoV) began in Wuhan, China and spread rapidly throughout the world. As of now, there have been numerous reports demonstrating clinical, radiological and pathological findings in adults. In children, the disease has essentially been seen as mild and self-limiting. However, more recently, children have been presenting with findings reminiscent of Kawasaki's disease. And secondary to this, the benign nature of COVID-19 disease in children is beginning to be challenged. This phenomenon is now referred to as multisystem inflammatory syndrome in children (MIS-C). Further understanding the clinical course in MIS-C and its temporal association with coronavirus disease 2019 will be paramount for treatment and public health decision making. This correspondence describes a case of MIS-C with gastrointestinal manifestations mimicking acute appendicitis in a child presenting from a COVID-19 endemic area.
新型冠状病毒（2019 - nCoV）疫情始于中国武汉，并迅速蔓延至全球。截至目前，已有大量报告展示了成人的临床、放射学和病理学表现。在儿童中，该疾病基本上被视为轻症且具有自限性。然而，最近儿童出现了类似川崎病的表现。由此，儿童COVID - 19疾病的良性性质开始受到挑战。这种现象现在被称为儿童多系统炎症综合征（MIS - C）。进一步了解MIS - C的临床病程及其与2019冠状病毒病的时间关联对于治疗和公共卫生决策至关重要。本信函描述了一例来自COVID - 19流行地区的儿童MIS - C病例，其胃肠道表现酷似急性阑尾炎。
