School of Engineering, Newcastle University, Newcastle Upon Tyne, UK.
Department of Oncology, University of Oxford, Oxford, UK.
Biotechnol Bioeng. 2021 Feb;118(2):918-929. doi: 10.1002/bit.27619. Epub 2020 Nov 18.
Biofilm streamer motion under different flow conditions is important for a wide range of industries. The existing work has largely focused on experimental characterisations of these streamers, which is often time-consuming and expensive. To better understand the physics of biofilm streamer oscillation and their interactions in fluid flow, a computational fluid dynamics-discrete element method model has been developed. The model was used to study the flow-induced oscillations and cohesive failure of single and multiple biofilm streamers. We have studied the effect of streamer length on the oscillation at varied flow rates. The predicted single biofilm streamer oscillations in various flow rates agreed well with experimental measurements. We have also investigated the effect of the spatial arrangement of streamers on interactions between two oscillating streamers in parallel and tandem arrangements. Furthermore, cohesive failure of streamers was studied in an accelerating fluid flow, which is important for slowing down biofilm-induced clogging.
生物膜流在不同流动条件下的运动对于广泛的行业都很重要。现有工作主要集中在这些流的实验特性上,这往往既耗时又昂贵。为了更好地了解生物膜流的振荡物理及其在流体流动中的相互作用,开发了计算流体动力学-离散元法模型。该模型用于研究单个和多个生物膜流的流致振荡和内聚破坏。我们研究了流率变化时流对振荡的影响。在各种流率下,预测的单个生物膜流的振荡与实验测量结果吻合较好。我们还研究了流的空间排列对平行和串联排列的两个振荡流之间相互作用的影响。此外,还研究了在加速流中流的内聚破坏,这对于减缓生物膜引起的堵塞很重要。