沙特阿拉伯儿科药物的产酸评估
Acidogenic Evaluation of Pediatric Medications in Saudi Arabia.
作者信息
Gowdar Inderjit M, Aldamigh Sulaiman A, Alnafisah Abdulrahman M, Wabran Mohammed S, Althwaini Abdullah S, Alothman Tamim A
机构信息
Department of Preventive Dental Sciences, College of Dentistry, Prince Sattam bin Abdulaziz University, Al-Kharj, Kingdom of Saudi Arabia.
College of Dentistry, Prince Sattam bin Abdulaziz University, Al-Kharj, Kingdom of Saudi Arabia.
出版信息
J Pharm Bioallied Sci. 2020 Aug;12(Suppl 1):S146-S150. doi: 10.4103/jpbs.JPBS_46_20. Epub 2020 Aug 28.
BACKGROUND
To gain patient compliance, pediatric medication preparations are made palatable by adding sugars such as sucrose, glucose, or fructose. These readily fermentable carbohydrates can significantly increase dental caries potential in the young and chronically sick children.
OBJECTIVES
To evaluate acidogenic potential of commonly used pediatric liquid medicaments (PLMs).
MATERIALS AND METHODS
The acidogenic potential is assessed by estimating the endogenous pH of PLM.
RESULTS
The mean endogenous pH was higher in Azomycin (9.16 ± 0.25) and lowest in Lorinase (3.16 ± 0.15).
CONCLUSION
Of nine, eight PLMs were acidic in nature.
背景
为了提高患者的依从性，儿科药物制剂通过添加蔗糖、葡萄糖或果糖等糖类使其口感更好。这些易于发酵的碳水化合物会显著增加年幼及慢性病患儿患龋齿的可能性。
目的
评估常用儿科液体药物（PLM）的产酸潜力。
材料与方法
通过估算PLM的内源性pH值来评估产酸潜力。
结果
阿佐霉素的平均内源性pH值最高（9.16±0.25），洛里那酶的最低（3.16±0.15）。
结论
九种PLM中，有八种本质上呈酸性。
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