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沙特阿拉伯王国常用儿科液体药物的致龋潜力:一项体外研究

Cariogenic Potential of the commonly Prescribed Pediatric Liquid Medicaments in Kingdom of Saudi Arabia: An in vitro Study.

作者信息

Gupta Megha, Panda Suman

机构信息

Department of Preventive Dental Sciences, Division of Pedodontics, College of Dentistry, Jazan University, Jazan Kingdom of Saudi Arabia, Phone: +00966536856649, e-mail:

Department of Preventive Dental Sciences, Division of Pedodontics, College of Dentistry, Jazan University, Jazan Kingdom of Saudi Arabia.

出版信息

J Contemp Dent Pract. 2017 Apr 1;18(4):307-311. doi: 10.5005/jp-journals-10024-2036.

Abstract

AIM

The aim of this study was to assess the cariogenic potential of the commonly prescribed pediatric liquid medicaments (PLMs) for dental disease in Jazan region, Kingdom of Saudi Arabia.

MATERIALS AND METHODS

Seven most commonly prescribed PLMs were selected by prior questioning the pediatric dentists as well as general dentists in Jazan region. The endogenous pH and sucrose concentrations of the liquid medicaments were assessed. The endogenous pH was assessed by Hanna pH meter instrument. The sucrose concentration was assessed by anthrone reagent method.

RESULTS

All the PLM were acidic. The pH of the PLM ranged from 4.22 to 6.10. All the PLM contained sucrose and its concentration ranged from 5.38 to 11.41 gm% in the samples.

CONCLUSION

In this study, all the PLM were acidic and contained sucrose. Hence, they have cariogenic potential.

CLINICAL SIGNIFICANCE

Parents and dentists are unaware of the hidden sugars and cariogenicity of these medications. Strict oral hygiene instructions are mandatory for the children taking these medications. The use of PLM should also be minimized and parents should seek early dental treatment to restore child's oral health.

摘要

目的

本研究旨在评估沙特阿拉伯王国吉赞地区常用的儿科液体药物(PLMs)对牙齿疾病的致龋潜力。

材料与方法

通过事先询问吉赞地区的儿科牙医和普通牙医,选取了七种最常用的PLMs。评估了液体药物的内源性pH值和蔗糖浓度。内源性pH值用汉纳pH计测定。蔗糖浓度用蒽酮试剂法测定。

结果

所有PLM均呈酸性。PLM的pH值范围为4.22至6.10。所有PLM均含有蔗糖,样品中蔗糖浓度范围为5.38至11.41克%。

结论

在本研究中,所有PLM均呈酸性且含有蔗糖。因此,它们有致龋潜力。

临床意义

家长和牙医未意识到这些药物中隐藏的糖分和致龋性。对于服用这些药物的儿童,严格的口腔卫生指导是必不可少的。还应尽量减少PLM的使用,家长应尽早寻求牙科治疗以恢复儿童的口腔健康。

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