Gandhi Shrimanikandan Ayappa, Chandrasekar Preetha, Nachimuthu Jayaprakash, Abraham Chris S, Venkataraman Karunakaran Jeyaraman
Department of Craniofacial Surgery & Dentistry, Velammal Medical Hospital & Research Institute, Madurai, Tamilnadu, India.
Department of Conservative Dentistry, JKK Nataraja Dental College & Hospital, Komarapalayam, Tamilnadu, India.
J Pharm Bioallied Sci. 2020 Aug;12(Suppl 1):S576-S582. doi: 10.4103/jpbs.JPBS_186_20. Epub 2020 Aug 28.
The aim of this study was to compare radicular smear layer removal ability of different solutions of phytic acid (PA) with other chelating agents when used in specific irrigant protocols.
Seventy four maxillary central incisors were collected, standardized, and canals were prepared. A total of 5% sodium hypochlorite was used as the initial rinse solution (8mL). Samples were divided into control (Group I-normal saline and II-7% ethylenediaminetetraacetic acid) and experimental groups (Group III, IV, V, VI, VII, and VIII) based on the type of final rinse solution used, that is, 5% PA, 10% PA, 17% PA, 5% citric acid (CA), 10% CA, and 17% CA (5mL). Samples were coded, buccolingually divided into two halves, dehydrated, mounted, splutter coated, and examined under scanning electron microscope.
Group IV had the least smear and debris in coronal, middle, and apical thirds with mean scores of 1.06 and 1.3, respectively. When compared with Group II, no statistically significant difference was found (P > 0.05). Overall, the Group III had the lowest erosion scores at apical, middle, and coronal one-third with a mean of 1.68. Group VII had the highest amount of erosion with loss of peritubular and intertubular dentin at all levels.
The role of PA as final rinse solution for the removal of radicular smear is promising and comparable to other chelating agents.
本研究旨在比较植酸(PA)不同溶液与其他螯合剂在特定冲洗方案中去除根管玷污层的能力。
收集74颗上颌中切牙,进行标准化处理并预备根管。使用5%次氯酸钠作为初始冲洗液(8mL)。根据最终冲洗液类型将样本分为对照组(I组 - 生理盐水和II组 - 7%乙二胺四乙酸)和实验组(III组、IV组、V组、VI组、VII组和VIII组),即5% PA、10% PA、17% PA、5%柠檬酸(CA)、10% CA和17% CA(5mL)。对样本进行编码,从颊舌向分为两半,脱水、包埋、溅射镀膜,然后在扫描电子显微镜下检查。
IV组在冠部、中部和根尖三分之一处的玷污层和碎屑最少,平均评分为1.06和1.3。与II组相比,未发现统计学上的显著差异(P>0.05)。总体而言,III组在根尖、中部和冠部三分之一处的侵蚀评分最低,平均为1.68。VII组的侵蚀量最大,在所有水平上均有管周和管间牙本质丧失。
PA作为根管冲洗的最终溶液在去除根管玷污层方面具有前景,且与其他螯合剂相当。