Department of Anaesthesia, Bristol Centre for Surgical Research, Bristol, UK.
Department of Vascular Surgery, Bristol Centre for Surgical Research, Bristol, UK.
Anaesthesia. 2021 Jun;76(6):832-836. doi: 10.1111/anae.15294. Epub 2020 Nov 5.
Interventions from randomised controlled trials can only be replicated if they are reported in sufficient detail. The results of trials can only be confidently interpreted if the delivery of the intervention was systematic and the protocol adhered to. We systematically reviewed trials of anaesthetic interventions published in 12 journals from January 2016 to September 2019. We assessed the detail with which interventions were reported, using the Consolidated Standards of Reporting Trials statement for non-pharmacological treatments. We analysed 162 interventions reported by 78 trials in 18,675 participants. Detail sufficiently precise to replicate the intervention was reported for 111 (69%) interventions. Intervention standardisation was reported for 135 (83%) out of the 162 interventions, and protocol adherence was reported for 20 (12%) interventions. Sixty (77%) out of the 78 trials reported the administrative context in which interventions were delivered and 36 (46%) trials detailed the expertise of the practitioners. We conclude that bespoke reporting tools should be developed for anaesthetic interventions and interventions in other areas such as critical care.
如果要对随机对照试验的干预措施进行复制,就必须对其进行充分详细的报告。只有当干预措施的实施是系统的,并且遵守了方案时,试验结果才能被自信地解释。我们系统地回顾了 2016 年 1 月至 2019 年 9 月期间在 12 种期刊上发表的麻醉干预试验。我们使用非药物治疗的 CONSORT 声明来评估干预措施报告的详细程度。我们分析了 18675 名参与者参与的 78 项试验中报告的 162 项干预措施。对于 111 项(69%)干预措施,报告的细节足够精确,可以对其进行复制。162 项干预措施中有 135 项(83%)报告了干预措施的标准化,20 项(12%)报告了方案的遵守情况。78 项试验中的 60 项(77%)报告了干预措施实施的行政背景,36 项(46%)试验详细说明了从业者的专业知识。我们的结论是,应该为麻醉干预措施以及其他领域(如重症监护)的干预措施开发定制的报告工具。