Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur 208016, U.P., India.
Department of Chemistry, Colorado School of Mines, Golden, Colorado 80401, USA.
Org Biomol Chem. 2020 Nov 28;18(44):9044-9049. doi: 10.1039/d0ob01697g. Epub 2020 Nov 5.
A synthetic method towards fluorinated allylamines using allene precursors is reported. A variety of heterocyclic amines were employed as nucleophiles in a Selectfluor promoted intermolecular fluoroamination reaction. This strategy provides a novel synthetic route to access vinyl fluorides with a vicinal amine moiety.
本文报道了一种使用丙二烯前体合成氟代烯丙胺的方法。各种杂环胺作为亲核试剂，在 Selectfluor 促进的分子间氟胺化反应中被使用。该策略提供了一种合成带有相邻胺基的乙烯基氟化物的新途径。
