Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.
Department of Small Animal Clinical Science, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
Vet Ophthalmol. 2020 Nov;23(6):1009-1013. doi: 10.1111/vop.12842. Epub 2020 Nov 5.
To determine whether bacteria are isolated from canine indolent ulcers and evaluate their influence on clinical outcomes.
Swabs for anaerobic and aerobic culture were collected from indolent ulcers of 43 client-owned dogs presenting to the University of Saskatchewan Veterinary Medical Centre. Outcomes were compared between ulcers with bacterial isolates and those without. Medical therapy was reviewed.
Bacteria were isolated in 8/43 ulcers: Three cultured two isolates and five cultured single isolates. Staphylococcus was the most common genus isolated and was present in six ulcers: Species included unspecified [2], pseudintermedius [2], schleiferi [1], and hominis [1]. Streptococcus was the second most common isolate present in two ulcers: Species included canis and agalactiae. Tobramycin was the most common antibiotic used in ulcers with bacterial isolates prior to referral (n = 3). One case did not have conclusive follow-up data from the referring veterinarian and was therefore excluded from further analysis. All seven culture-positive ulcers were recorded as healed without complication: six healing after one procedure and one healing after two procedures. Thirty-five ulcers were culture-negative. There was no difference in outcome between indolent ulcers with bacterial isolates and those with negative cultures (P = .7475).
Bacteria were isolated from 19% of indolent ulcers, and Staphylococcus was the most common isolate. Bacterial isolation did not influence outcome.
确定犬慢性溃疡中是否分离出细菌，并评估其对临床结果的影响。
从 43 只就诊于萨斯喀彻温省大学兽医学院的患犬的慢性溃疡中采集厌氧和需氧培养拭子。比较有细菌分离物和无细菌分离物的溃疡的结果。回顾了医学治疗。
8/43 个溃疡分离出细菌：3 个培养出两种分离物，5 个培养出单一分离物。葡萄球菌是最常见的分离菌属，存在于 6 个溃疡中：包括未指定的 [2]、中间葡萄球菌[2]、施氏葡萄球菌 [1] 和人葡萄球菌[1]。链球菌是存在于 2 个溃疡中的第二种最常见的分离物：包括犬链球菌和无乳链球菌。妥布霉素是在转诊前有细菌分离物的溃疡中最常用的抗生素（n=3）。有 1 例没有从转诊兽医那里获得明确的随访数据，因此被排除在进一步分析之外。所有 7 个培养阳性的溃疡均记录为无并发症愈合：6 个在一次治疗后愈合，1 个在两次治疗后愈合。35 个溃疡培养阴性。有细菌分离物和无细菌分离物的慢性溃疡的结果无差异（P=0.7475）。
19%的慢性溃疡分离出细菌，葡萄球菌是最常见的分离物。细菌分离并不影响结果。
