稳定性冠心病患者临床SYNTAX评分II与颈动脉内膜中层厚度之间的实际相关性。
A real-life correlation between clinical SYNTAX score II and carotid intima-media thickness in patients with stable coronary artery disease.
作者信息
Abdelnabi Mahmoud, Almaghraby Abdallah, Tok Özge Özden, Öz Tuğba Kemaloğlu, Saleh Yehia, Morsi Ahmed, Badran Hiatham
机构信息
Cardiology and Angiology Unit, Department of Clinical and Experimental Internal Medicine, Medical Research Institute, University of Alexandria, Alexandria, Egypt.
Department of Cardiology, Faculty of Medicine, University of Alexandria, Alexandria, Egypt.
出版信息
J Saudi Heart Assoc. 2020 Apr 17;32(1):8-11. doi: 10.37616/2212-5043.1002. eCollection 2020.
BACKGROUND
SYNTAX score II (SSII) is an update of the established SYNTAX score (SS) that uses clinical variables such as age, sex, creatinine clearance, left ventricular ejection fraction, chronic obstructive pulmonary disease, and peripheral arterial disease. Furthermore, SSII has been proven to be a more powerful predictive tool than SS in patients with complex coronary artery disease (CAD). Carotid õntima-media thickness (CIMT) is a widely used noninvasive evidence for subclinical or early atherosclerosis, and it was proved to be an independent predictor for cardiovascular events. Most of the previously published articles studied the association between the CIMT with old cardiovascular scoring systems such as SSI and Gensini score with debatable data about their correlation.
AIM
To study the correlation between SSII and CIMT in stable CAD patients undergoing elective coronary angiography (CA).
METHOD AND PATIENTS
A prospective study including 155 patients undergoing elective CA for stable CAD excluding patients with history of acute coronary syndrome, previous coronary revascularization either by percutaneous coronary intervention or coronary artery bypass grafting, and previous cerebrovascular stroke.
RESULTS
The mean age of patients was 58.25 ± 16.46 years, and 79 patients (50.96%) were men. The mean SSII score was 10.23 ± 11.36 and mean CIMT was 0.85 ± 0.24. The correlation between SSII and CIMT using Spearman correlation showed a strong correlation between SSII score and CIMT with correlation coefficient = 0.752.
CONCLUSION
The study showed a strong positive correlation between SSII and CIMT in stable CAD patients undergoing elective CA.
背景
SYNTAX评分II（SSII）是既定的SYNTAX评分（SS）的升级版，它使用年龄、性别、肌酐清除率、左心室射血分数、慢性阻塞性肺疾病和外周动脉疾病等临床变量。此外，在复杂冠状动脉疾病（CAD）患者中，SSII已被证明是比SS更强大的预测工具。颈动脉内膜中层厚度（CIMT）是用于亚临床或早期动脉粥样硬化的一种广泛使用的无创证据，并且它被证明是心血管事件的独立预测因子。大多数先前发表的文章研究了CIMT与诸如SSI和Gensini评分等旧的心血管评分系统之间的关联，但其相关性数据存在争议。
目的
研究接受择期冠状动脉造影（CA）的稳定CAD患者中SSII与CIMT之间的相关性。
方法和患者
一项前瞻性研究，纳入155例因稳定CAD接受择期CA的患者，排除有急性冠状动脉综合征病史、既往经皮冠状动脉介入治疗或冠状动脉旁路移植术进行冠状动脉血运重建病史以及既往有脑血管卒中病史的患者。
结果
患者的平均年龄为58.25±16.46岁，79例（50.96%）为男性。平均SSII评分为10.23±11.36，平均CIMT为0.85±0.24。使用Spearman相关性分析SSII与CIMT之间的相关性，结果显示SSII评分与CIMT之间存在强相关性，相关系数=0.752。
结论
该研究表明，在接受择期CA的稳定CAD患者中，SSII与CIMT之间存在强正相关。
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