Columbia University, New York, NY 10032, USA.
Cell Stem Cell. 2020 Nov 5;27(5):697-698. doi: 10.1016/j.stem.2020.10.009.
Extracellular matrix is known to regulate vascularization by a sequence of multiple factors including mechanical forces. In this issue of Cell Stem Cell, Wei et al. (2020) investigate the roles of matrix biomechanics on early stages of vasculogenesis by using hydrogels with tunable stiffness and stress relaxation.
细胞外基质通过一系列的多种因素(包括机械力)来调节血管生成。在本期的《Cell Stem Cell》杂志中,Wei 等人(2020 年)通过使用具有可调刚度和应力松弛的水凝胶来研究基质生物力学在血管发生早期阶段的作用。