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验证移动口头学习测试:说明其在年龄和疾病相关认知缺陷中的应用。

Validation of the mobile verbal learning test: Illustration of its use for age and disease-related cognitive deficits.

机构信息

Department of Psychiatry, University of California San Diego, San Diego, California, USA.

SDSU/UC San Diego Joint Doctoral Program in Clinical Psychology, San Diego, California, USA.

出版信息

Int J Methods Psychiatr Res. 2021 Mar;30(1):e1859. doi: 10.1002/mpr.1859. Epub 2020 Nov 7.

DOI:10.1002/mpr.1859
PMID:33159488
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7992286/
Abstract

OBJECTIVE

We developed a mobile cognitive test of verbal learning and memory, the mobile verbal learning test (mVLT), to allow for brief, repeated and portable delivery of a 12-item list learning test through a smartphone. This study examined the psychometric properties of the mVLT among older persons with and without human immunodeficiency virus (HIV).

METHODS

Sixty-eight persons with HIV and 36 HIV-negative individuals (aged 50-74) completed three trials of the mVLT on a smartphone once daily for 14 days. A different word list was administered each day.

RESULTS

Participants completed 80% of the 14 mVLT administrations, equating to 1166 valid and complete mVLTs. Neither adherence nor mean mVLT total score (number correct in 3 recall trials) differed by HIV status. No practice effects from repeated mVLT administration were observed, and there were moderately strong correlations of mVLT performance with performance on the in-lab version of the task and with traditional cognitive assessments of cognitive processes contributing to memory. We found evidence of within-person learning across mVLT trials, with persons with HIV demonstrating less learning from trials 1 to 3 compared to HIV-negative participants.

CONCLUSIONS

The mVLT is a valid method to assess learning in the real world in older adults with and without HIV.

摘要

目的

我们开发了一种移动的言语学习和记忆认知测试,即移动言语学习测试(mVLT),以便通过智能手机进行简短、重复和便携的 12 项列表学习测试。本研究考察了 mVLT 在伴有和不伴有人类免疫缺陷病毒(HIV)的老年人中的心理测量特性。

方法

68 名 HIV 感染者和 36 名 HIV 阴性个体(年龄 50-74 岁)每天在智能手机上完成三次 mVLT 测试,共 14 天。每天使用不同的单词列表。

结果

参与者完成了 14 次 mVLT 测试中的 80%,相当于完成了 1166 次有效和完整的 mVLT 测试。HIV 状态既不影响依从性,也不影响 mVLT 总分(3 次回忆测验中正确的数量)。重复进行 mVLT 测试并没有观察到练习效应,并且 mVLT 表现与实验室版本任务以及对记忆相关认知过程的传统认知评估之间存在中度强相关性。我们发现了在 mVLT 测试中存在个体内学习的证据,与 HIV 阴性参与者相比,HIV 感染者在第 1 到 3 次测试中学习较少。

结论

mVLT 是一种在伴有和不伴有 HIV 的老年人中评估现实世界学习能力的有效方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c05a/7992286/65db0d4ca706/MPR-30-e1859-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c05a/7992286/9a77cc2c1def/MPR-30-e1859-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c05a/7992286/1ab9caed5690/MPR-30-e1859-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c05a/7992286/65db0d4ca706/MPR-30-e1859-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c05a/7992286/9a77cc2c1def/MPR-30-e1859-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c05a/7992286/1ab9caed5690/MPR-30-e1859-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c05a/7992286/65db0d4ca706/MPR-30-e1859-g003.jpg

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