Judd R L
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia.
Hum Pathol. 1987 Nov;18(11):1180-3. doi: 10.1016/s0046-8177(87)80388-x.
A 12-year-old boy with massive true thymic hyperplasia presented with respiratory distress and dysphagia. The thymus weighed 245 g and demonstrated normal cortical and medullary components histologically. The findings in this case were compared with the clinical and pathologic features of seven previously published cases of massive hyperplasia and with cases of mild or "borderline" hyperplasia. By electron microscopy and immunoperoxidase techniques, myoid cell differentiation was demonstrated, the first documented example of myoid cells in thymic hyperplasia. These findings support the hypothesis that myoid cells are a normal component of thymic parenchyma.
一名12岁男孩患有巨大真性胸腺增生，表现为呼吸窘迫和吞咽困难。胸腺重245克，组织学检查显示皮质和髓质成分正常。将该病例的发现与之前发表的7例巨大增生病例以及轻度或“临界”增生病例的临床和病理特征进行了比较。通过电子显微镜和免疫过氧化物酶技术，证实了肌样细胞分化，这是胸腺增生中肌样细胞的首个记录实例。这些发现支持了肌样细胞是胸腺实质正常成分的假说。
