Linegar A G, Odell J A, Fennell W M, Close P M, De Groot M K, Casserly D R, Perold J I
Department of Cardiothoracic Surgery, University of Cape Town, South Africa.
Ann Thorac Surg. 1993 May;55(5):1197-201. doi: 10.1016/0003-4975(93)90033-e.
Massive thymic hyperplasia is an extremely rare form of true thymic hyperplasia most often described in infants and children. Hyperplasia of this order is not known to occur in any other organ, and its etiology and prognostic significance remain unknown. As there is no accurate way of preoperatively differentiating massive thymic hyperplasia from other tumors of the thymus and anterior mediastinum, we advise excision in all cases for histological analysis and relief of mediastinal compression. This description of 4 cases updates the 30 previously reported cases, and includes a literature review.
巨大胸腺增生是一种极为罕见的真性胸腺增生形式，多见于婴幼儿及儿童。这种程度的增生在其他任何器官均未发现，其病因及预后意义尚不明确。由于术前尚无准确方法区分巨大胸腺增生与其他胸腺及前纵隔肿瘤，我们建议对所有病例进行切除，以进行组织学分析并缓解纵隔压迫。本文对4例病例的描述更新了之前报道的30例病例，并包括文献综述。
