Arul P, Huang Sheng-Tung, Gowthaman N S K, Govindasamy Mani, Jeromiyas Nithiya
Institute of Biochemical and Biomedical Engineering, Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei, 106, Taiwan.
Materials Synthesis and Characterization Laboratory, Institute of Advanced Technology, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
Mikrochim Acta. 2020 Nov 9;187(12):650. doi: 10.1007/s00604-020-04631-x.
A copper-1,4-naphthalenedicarboxylic acid-based organic framework (Cu-NDCA MOF) with different morphologies was synthesized by solvothermal synthetic route via a simple protonation-deprotonation approach. The synthesized Cu-NDCA MOFs were analyzed by diverse microscopic and spectral techniques. The FE-SEM and TEM image results exhibited the flake-like (FL), partial anisotropic (PAT), and anisotropic (AT)-Cu-NDCA MOFs formation obtained at different pH (3.0, 7.0, and 9.0) of the reaction medium. The AT-Cu-NDCA MOF/GC electrode not only increases the electroactive surface area but also boosts the electron transfer rate reaction compared to other modified electrodes (PAT- and FL-Cu-NDCA MOFs/GCEs). Under the optimized conditions, the modified electrode (AT-Cu-NDCA MOF) exhibited a sharp oxidation peak (+ 0.46 V vs. Ag/AgCl) and higher current response for rutin. The electrode provides a wide linear range from 1 × 10 to 50 × 10 M, a low detection limit of 1.21 × 10 M, LOQ of 0.001 μM, and sensitivity of 0.149 μA μM cm. The AT-Cu-NDCA MOF/GC electrode exhibited good stability (RSD = 3.52 ± 0.02% over 8 days of storage), and excellent reproducibility (RSD = 2.62 ± 0.02% (n = 3)). The modified electrode was applied to the determination of rutin in apple, orange, and lemon samples with good recoveries (99.79-99.91, 99.24-99.69, and 99.53-99.83, respectively). Graphical abstract Anisotropic structure of Cu-NDCA MOFs and its modification on glassy carbon electrode for ultra-sensitive determination of rutin in fruit samples.
通过简单的质子化-去质子化方法，采用溶剂热合成路线合成了具有不同形态的基于1,4-萘二甲酸铜的有机框架（Cu-NDCA MOF）。通过多种显微镜和光谱技术对合成的Cu-NDCA MOF进行了分析。场发射扫描电子显微镜（FE-SEM）和透射电子显微镜（TEM）图像结果显示，在反应介质的不同pH值（3.0、7.0和9.0）下获得了片状（FL）、部分各向异性（PAT）和各向异性（AT）的Cu-NDCA MOF。与其他修饰电极（PAT-和FL-Cu-NDCA MOF/GCE）相比，AT-Cu-NDCA MOF/GC电极不仅增加了电活性表面积，还提高了电子转移速率反应。在优化条件下，修饰电极（AT-Cu-NDCA MOF）对芦丁表现出尖锐的氧化峰（相对于Ag/AgCl为+0.46 V）和更高的电流响应。该电极提供了从1×10到50×10 M的宽线性范围、1.21×10 M的低检测限、0.001 μM的定量限和0.149 μA μM cm的灵敏度。AT-Cu-NDCA MOF/GC电极表现出良好的稳定性（储存8天的相对标准偏差RSD = 3.52±0.02%）和出色的重现性（RSD = 2.62±0.02%（n = 3））。该修饰电极应用于苹果、橙子和柠檬样品中芦丁的测定，回收率良好（分别为99.79-99.91、99.24-99.69和99.53-99.83）。图形摘要Cu-NDCA MOF的各向异性结构及其对玻碳电极的修饰用于水果样品中芦丁的超灵敏测定。
