Ikegaya H, Iwasaki T, Matsuda I, Satodate R, Sasou S
Dept. of Obstetrics & Gynecology, Red Cross Hospital in Morioka.
Gan No Rinsho. 1987 Oct;33(12):1515-23.
A case of a primary amelanotic melanoma of the vagina is reported. The patient was a 58-year-old Japanese female. A polypoid tumor was found on the lateral wall of the vagina and a cytologic examination of a scraping showed a few large atypical cells with cleaved nuclei and intranuclear vacuoles. A lateral junctional spread was histologically observed and stage II melanosomes were found in the cytoplasm. Two years after a radical operation, the patient died of a widespread melanotic metastases. The authors survey the number of incidences of malignant melanoma in the female genital organ. In Japanese women, melanoma is seen more frequently in the vagina than in the vulva, which is quite the opposite in cases of malignant melanomas of the genital organs in women of the United States and Europe.
报告了一例原发性阴道无色素性黑色素瘤病例。患者为一名58岁的日本女性。在阴道侧壁发现一个息肉样肿瘤，刮片细胞学检查显示有一些大的非典型细胞，核有切迹且核内有空泡。组织学观察到侧向交界性扩散，在细胞质中发现了II期黑素小体。根治性手术后两年，患者死于广泛的黑色素转移。作者调查了女性生殖器官恶性黑色素瘤的发病率。在日本女性中，黑色素瘤在阴道的发病率高于在外阴，这与美国和欧洲女性生殖器官恶性黑色素瘤的情况正好相反。
