Biomedical Sciences Department, College of Medicine and Health Sciences, Adigrat University, Adigrat, Ethiopia.
Medical Physiology Department, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
PLoS One. 2020 Nov 10;15(11):e0240678. doi: 10.1371/journal.pone.0240678. eCollection 2020.
Patients with Diabetic Mellitus are at higher risk of different complications. Many previous studies show that anemia among diabetic patients is poorly diagnosed.
This study aimed to assess the magnitude and associated factors of anemia among adult diabetes patients having regular follow up at the diabetic clinic of Ayder Comprehensive Specialized Hospital, Tigray, 2018/19.
This study was conducted the Diabetic clinic of Ayder comprehensive specialized hospital, Tigray regional state, Northern Ethiopia from January to March 2019. A systematic random sampling technique was used to select study participants. About 5 ml of venous blood was collected by experienced laboratory technologists under a complete aseptic technique. Two ml of the venous blood was used for hemoglobin determination. And three ml of the venous blood was used without any anticoagulant for creatinine determination. The association of variables was assessed using bivariate and multivariable analysis in the logistic regression model with p-value, odds ratio, and 95% CI in the SPSS version 24 software.
From a total of 262 diabetes patients, forty-seven (17.9%) were found to be anemic (6.7% males and 11.5% females). Among the related factors, residency (Adjusted Odds Ratio, 7.69, 95% CI, 2.060, 28.69, p = 0.002,), age of the patients (Adjusted Odds Ratio, 4.007, 95%CI, 1.53-10.51, p = 0.005,) and sex (Adjusted Odds Ratio, 3.434, 95% CI, 1.582, 7.458, p = 0.042,) were significantly associated with anemia.
According to this study, the magnitude of anemia is high among diabetic patients. Occupation of the participants, residency, HIV status, being female, and age was significantly associated with anemia.
糖尿病患者有发生各种并发症的较高风险。许多先前的研究表明，糖尿病患者的贫血常常被漏诊。
本研究旨在评估在提格雷州阿德尔综合专科医院糖尿病诊所定期就诊的成年糖尿病患者贫血的严重程度及其相关因素。
本研究于 2019 年 1 月至 3 月在埃塞俄比亚北部提格雷州阿德尔综合专科医院的糖尿病诊所进行。采用系统随机抽样技术选择研究对象。在完全无菌的技术下，由经验丰富的实验室技术人员采集约 5 毫升静脉血。用其中 2 毫升静脉血测定血红蛋白，用 3 毫升未加抗凝剂的静脉血测定肌酐。使用逻辑回归模型中的 b ivariate 和 multivariable 分析评估变量之间的关联，p 值、比值比和 95%CI 在 SPSS 版本 24 软件中得出。
在总共 262 名糖尿病患者中，有 47 名（17.9%）被诊断为贫血（男性占 6.7%，女性占 11.5%）。在相关因素中，居住地（调整后的比值比，7.69，95%置信区间，2.060，28.69，p = 0.002）、患者年龄（调整后的比值比，4.007，95%置信区间，1.53-10.51，p = 0.005）和性别（调整后的比值比，3.434，95%置信区间，1.582，7.458，p = 0.042）与贫血显著相关。
根据本研究，糖尿病患者贫血的发生率较高。参与者的职业、居住地、HIV 状况、性别和年龄与贫血显著相关。
