a Department of Biomedical Laboratory Science , Hanlyo University , Gwangyang-si , South Korea.
b Department of Biomedical Laboratory Science , Wonkwang Health Science University , Iksan-si , South Korea.
Clin Exp Hypertens. 2018;40(7):650-655. doi: 10.1080/10641963.2017.1416123. Epub 2018 Jan 10.
The present study was conducted to assess the relationship between anemia and pulse pressure (PP) and hypertension (HTN). Data from 16,060 adults (aged ≥20 years) in the fifth Korean National Health and Nutrition Examination Survey (2010-2012) were analyzed. Several key findings were identified. First, after adjusting for related variables, the odds ratio (OR) of anemia (hemoglobin <13 and <12 g/dL, in men and women, respectively), using the normal PP group (PP ≤61 mmHg) as a reference, was significant for the high PP cohort (PP >61 mmHg; OR, 1.517; 95% confidence interval [CI], 1.270-1.812). Second, after adjusting for related variables (except body mass index [BMI] and waist measurement [WM]), the OR of anemia, with a normal blood pressure group as a reference, was significant for the HTN group (systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg or use of HTN medications; OR, 0.835; 95% CI, 0.709-0.983). However, when further adjusted for BMI and WM, anemia was not associated with HTN (OR, 0.884; 95% CI, 0.750-1.042). In conclusion, anemia was positively associated with high PP, but was not associated with HTN.
本研究旨在评估贫血与脉压（PP）和高血压（HTN）之间的关系。分析了来自第五次韩国国家健康和营养检查调查（2010-2012 年）的 16060 名成年人（年龄≥20 岁）的数据。得出了一些重要发现。首先，在校正了相关变量后，贫血（血红蛋白<13 和<12 g/dL，分别为男性和女性）的优势比（OR），以正常 PP 组（PP≤61mmHg）为参照，对高 PP 组（PP>61mmHg；OR，1.517；95%置信区间[CI]，1.270-1.812）具有统计学意义。其次，在校正了相关变量（除体重指数[BMI]和腰围测量[WM]外）后，以正常血压组为参照，贫血与 HTN 组的 OR 具有统计学意义（收缩压≥140mmHg 或舒张压≥90mmHg 或使用 HTN 药物；OR，0.835；95%CI，0.709-0.983）。然而，当进一步校正 BMI 和 WM 后，贫血与 HTN 无关（OR，0.884；95%CI，0.750-1.042）。总之，贫血与高 PP 呈正相关，但与 HTN 无关。
