Development of Antimicrobial Therapy Methods to Overcome the Antibiotic Resistance of Acinetobacter baumannii.

The spread of antibiotic resistance among pathogens represents a threat to human health around the world. In 2017, the World Health Organization published a list of 12 top-priority antibiotic-resistant pathogenic bacteria for which new effective antibiotics or new ways of treating the infections caused by them are needed. This review focuses on , one of these top-priority pathogens. The pathogenic bacterium is one of the most frequently encountered infectious agents in the world; its clinically significant features include resistance to UV light, drying, disinfectants, and antibiotics. This review looks at the various attempts that have been made to tackle the problem of drug resistance relating to variants without the use of antibiotics. The potential of bacteriophages and antimicrobial peptides in the treatment of infections caused by in both planktonic and biofilm form is assessed. Such topics as research into the development of vaccines based on the outer membrane proteins of and the use of silver nanoparticles, as well as photodynamic and chelate therapy, are also covered.