Vaez H, Ghanbari F, Sahebkar A, Khademi F
Department of Microbiology, School of Medicine, Zabol University of Medical Sciences, Zabol, Iran.
Student Research Committee, School of Medicine, Shahid Saddoughi University of Medical Sciences, Yazd, Iran.
Iran J Vet Res. 2020 Summer;21(3):188-197.
infection (salmonellosis) is a zoonotic bacterial disease. Widespread use of antibiotics in livestock and poultry production for different purposes such as treatment and growth promotion has led to the emergence of antibiotic-resistant , causing treatment of infections more difficult with each passing year.
To determine the antibiotic resistance prevalence of serotypes isolated from animals in different provinces of Iran.
To find eligible articles, we searched the international and national electronic databases using appropriate keywords in English and Persian.
After applying predefined criteria, 54 articles reporting antibiotic resistance profiles of serotypes were included. isolates were mostly resistant against nalidixic acid (67%), tetracycline (66.9%), and streptomycin (49.6%), followed by trimethoprim/sulfamethoxazole (41.6%) and kanamycin (23.6%). The highest sensitivity was observed against imipenem, meropenem, and cefepime with 1.7%, 1.4%, and 1.9% of all isolates being resistant, respectively.
Results revealed that the prevalence of resistant isolates to nalidixic acid, tetracycline and streptomycin is high and their use must be restricted. In addition, resistance to other antibiotics such as chloramphenicol, ampicillin, cephalothin, cefixime, and enrofloxacin is at an alarming level that calls for attention in the future infection control and antibiotic stewardship programs.
感染（沙门氏菌病）是一种人畜共患的细菌性疾病。在畜禽生产中出于治疗和促进生长等不同目的广泛使用抗生素，已导致抗生素耐药性的出现，使得感染的治疗逐年变得更加困难。
确定从伊朗不同省份的动物中分离出的沙门氏菌血清型的抗生素耐药性流行情况。
为找到符合条件的文章，我们使用英文和波斯文的适当关键词搜索了国际和国家电子数据库。
应用预定义标准后，纳入了54篇报告沙门氏菌血清型抗生素耐药性概况的文章。沙门氏菌分离株大多对萘啶酸（67%）、四环素（66.9%）和链霉素（49.6%）耐药，其次是甲氧苄啶/磺胺甲恶唑（41.6%）和卡那霉素（23.6%）。观察到对亚胺培南、美罗培南和头孢吡肟的敏感性最高，所有分离株中分别有1.7%、1.4%和1.9%对其耐药。
结果显示，对萘啶酸、四环素和链霉素耐药的分离株流行率很高，必须限制它们的使用。此外，对氯霉素、氨苄西林、头孢噻吩、头孢克肟和恩诺沙星等其他抗生素的耐药性处于令人担忧的水平，这在未来的感染控制和抗生素管理计划中需要引起关注。
