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伴有引流窦道的慢性人工关节感染。谁应该接受抑制性抗生素治疗?

Chronic prosthetic joint infections with a draining sinus. Who should receive suppressive antibiotic treatment?

作者信息

Lensen Karel-Jan, Escudero-Sanchez Rosa, Cobo Javier, Soriano Alex, Wouthuyzen-Bakker Marjan

机构信息

Department of Infectious Diseases, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

Department of Infectious Diseases, Hospital Ramón y Cajal, IRYCIS, Madrid, Spain.

出版信息

J Bone Jt Infect. 2020 Oct 30;6(2):43-45. doi: 10.5194/jbji-6-43-2020. eCollection 2020.

Abstract

The benefit of suppressive antibiotic treatment in inoperable patients with a chronic periprosthetic joint infection and a sinus tract is unknown. Some physicians prefer to just let the sinus drain, while others prefer antibiotic treatment. In this viewpoint article we discuss the advantages and disadvantages of suppressive antibiotic treatment in this particular patient group.

摘要

对于患有慢性人工关节周围感染且有窦道的无法手术的患者,抑制性抗生素治疗的益处尚不清楚。一些医生倾向于仅让窦道引流,而另一些医生则倾向于进行抗生素治疗。在这篇观点文章中,我们讨论了在这一特定患者群体中进行抑制性抗生素治疗的利弊。

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本文引用的文献

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Life-long antimicrobial therapy: where is the evidence?终身抗菌治疗:证据在哪里?
J Antimicrob Chemother. 2018 Oct 1;73(10):2601-2612. doi: 10.1093/jac/dky174.
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Long-term suppression of infection in total joint arthroplasty.全关节置换术中感染的长期抑制
Clin Orthop Relat Res. 2003 Sep(414):55-60. doi: 10.1097/01.blo.0000087321.60612.cf.
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Prolonged suppressive antibiotic therapy for infected orthopedic prostheses.
Clin Infect Dis. 1998 Oct;27(4):711-3. doi: 10.1086/514951.

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