Nascimento Dahan da Cunha, Prestes Jonato, de Sousa Diniz Joyce, Beal Pedro Rodrigues, Alves Vicente Paulo, Stone Whitley, Beal Fabiani Lage Rodrigues
Department of Physical Education, Catholic University of Brasilia (UCB), Brasilia, Brazil.
Department of Physical Education, Center University of Distrito Federal (UDF), Brasilia, Brazil.
J Exerc Rehabil. 2020 Oct 27;16(5):458-466. doi: 10.12965/jer.2040668.334. eCollection 2020 Oct.
Muscle quality (the ratio of strength to lean muscle mass) might be a better indicator of muscle function than strength alone. Differences in muscle quality index (MQI) between octogenarians and young older adults remain unclear. The aims of the present cross-sectional study were to compare (1) MQI between octogenarians and young older adults, (2) lab versus field-based MQI tools, and (3) determine possible confounding factors affecting MQI in older adults. Compiled data from two cross-sectional studies included 175 younger and older adults (31 men and 144 women) with a mean age of 75.93±9.49 years. Participants with age ≥80 years old were defined as octogenarians (n=79) and <80 years was defined as young older adults (n=96). Laboratory MQI was derived from the ratio of grip strength to arm muscle mass (in kg) measured by dual-energy x-ray absorptiometry. Field-based MQI was quantified from the ratio of grip strength to body mass index (BMI). Octogenarians displayed lower field (=0.003) and laboratory MQI (<0.001) as compared with young older adults. There was a strong correlation effect between field MQI and laboratory MQI (=0.001, =0.85). BMI (=0.001), and diabetes mellitus (=0.001) negatively affected MQI. Women presented lower MQI (=0.001) values than men. In light of this information, rehabilitation specialists should consider the use of field-based MQI as a tool for evaluation and follow-up of older population.
肌肉质量（力量与瘦肌肉量的比值）可能比单纯的力量更能准确反映肌肉功能。八旬老人与年轻老年人之间的肌肉质量指数（MQI）差异尚不清楚。本横断面研究的目的是比较：（1）八旬老人与年轻老年人之间的MQI；（2）实验室与基于现场的MQI工具；（3）确定影响老年人MQI的可能混杂因素。两项横断面研究汇总的数据包括175名年轻人和老年人（31名男性和144名女性），平均年龄为75.93±9.49岁。年龄≥80岁的参与者被定义为八旬老人（n=79），<80岁被定义为年轻老年人（n=96）。实验室MQI来自握力与通过双能X线吸收法测量的手臂肌肉质量（以千克为单位）的比值。基于现场的MQI通过握力与体重指数（BMI）的比值进行量化。与年轻老年人相比，八旬老人的现场MQI（=0.003）和实验室MQI（<0.001）较低。现场MQI与实验室MQI之间存在很强的相关性（=0.001，=0.85）。BMI（=0.001）和糖尿病（=0.001）对MQI有负面影响。女性的MQI值（=0.001）低于男性。鉴于这些信息，康复专家应考虑使用基于现场的MQI作为评估和随访老年人群的工具。
