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上消化道癌症中的影像生物标志物

Imaging biomarkers in upper gastrointestinal cancers.

作者信息

Gabelloni Michela, Faggioni Lorenzo, Neri Emanuele

机构信息

Department of Translational Research, Diagnostic and Interventional Radiology, University of Pisa, Pisa, Italy.

出版信息

BJR Open. 2019 Jun 24;1(1):20190001. doi: 10.1259/bjro.20190001. eCollection 2019.

Abstract

In parallel with the increasingly widespread availability of high performance imaging platforms and recent progresses in pathobiological characterisation and treatment of gastrointestinal malignancies, imaging biomarkers have become a major research topic due to their potential to provide additional quantitative information to conventional imaging modalities that can improve accuracy at staging and follow-up, predict outcome, and guide treatment planning in an individualised manner. The aim of this review is to briefly examine the status of current knowledge about imaging biomarkers in the field of upper gastrointestinal cancers, highlighting their potential applications and future perspectives in patient management from diagnosis onwards.

摘要

随着高性能成像平台的日益普及以及胃肠道恶性肿瘤病理生物学特征描述和治疗方面的最新进展,成像生物标志物已成为一个主要的研究课题,因为它们有可能为传统成像方式提供额外的定量信息,从而提高分期和随访的准确性、预测预后并以个体化方式指导治疗计划。本综述的目的是简要审视上消化道癌症领域中成像生物标志物的当前知识状况,重点介绍其在从诊断开始的患者管理中的潜在应用和未来前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c1c/7592483/6a0a44596ca2/bjro.20190001.g001.jpg

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