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Insights into malaria pathogenesis gained from host metabolomics.

作者信息

Colvin Heather N, Joice Cordy Regina

机构信息

Department of Biology, Wake Forest University, Winston-Salem, North Carolina, United States of America.

Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.

出版信息

PLoS Pathog. 2020 Nov 12;16(11):e1008930. doi: 10.1371/journal.ppat.1008930. eCollection 2020 Nov.

DOI:10.1371/journal.ppat.1008930
PMID:33180883
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7660577/
Abstract
摘要

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A First Natural Infection Induces Increased Activity of the Interferon Gamma-Driven Tryptophan Catabolism Pathway.初次自然感染会诱导干扰素γ驱动的色氨酸分解代谢途径的活性增加。
Front Microbiol. 2020 Mar 17;11:400. doi: 10.3389/fmicb.2020.00400. eCollection 2020.
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Mining the Human Host Metabolome Toward an Improved Understanding of Malaria Transmission.
复发性间日疟原虫感染的宿主代谢组学反应。
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Amino acid supplementation confers protection to red blood cells before Plasmodium falciparum bystander stress.氨基酸补充在恶性疟原虫旁观者应激前对红细胞提供保护。
Blood Adv. 2024 May 28;8(10):2552-2564. doi: 10.1182/bloodadvances.2023010820.
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Alignment of multiple metabolomics LC-MS datasets from disparate diseases to reveal fever-associated metabolites.将来自不同疾病的多个代谢组学 LC-MS 数据集进行对齐，以揭示与发热相关的代谢物。
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