El-Allaky Hend S, Wahba Nadia A, Talaat Dalia M, Zakaria Azza S
J Clin Pediatr Dent. 2020 Sep 1;44(5):289-295. doi: 10.17796/1053-4625-44.5.1.
To investigate the effect of two methods of propolis administration on plaque accumulation and microbial count as well as patient acceptance of each vehicle.
A randomized clinical trial with two parallel arms was used with a sample of 60 high caries risk children 6-8 years old. Children were divided randomly into two groups. Group I: Children who received propolis chewing gum and instructed to chew it twice daily for at least twenty minutes, for two weeks. Group II: children who received propolis mouthwash and instructed to rinse twice daily for one minute. A plaque index was recorded and a plaque sample was collected from all participants at base line and after two weeks of treatment. All participants were asked to rate the preparation they received during treatment period on a Visual Analogue Scale chart.
Data showed that propolis had a significant effect on reducing plaque scores and colony counts in both vehicles. There was no significant difference between both vehicles neither on plaque reduction nor on microbial count. However children preferred the gum formula.
Propolis in both vehicles reduced plaque accumulation and microbial count which recommends its use as an antimicrobial agent in different vehicles.
研究两种蜂胶给药方法对菌斑积聚、微生物数量的影响以及患者对每种剂型的接受程度。
采用随机平行双臂临床试验，样本为60名6 - 8岁高龋风险儿童。儿童被随机分为两组。第一组：接受蜂胶口香糖的儿童，每天咀嚼两次，每次至少20分钟，持续两周。第二组：接受蜂胶漱口水的儿童，每天漱口两次，每次1分钟。记录菌斑指数，并在基线和治疗两周后从所有参与者处采集菌斑样本。所有参与者被要求在视觉模拟量表上对他们在治疗期间所接受的制剂进行评分。
数据显示，蜂胶对两种剂型的菌斑评分和菌落计数均有显著降低作用。两种剂型在减少菌斑和微生物数量方面均无显著差异。然而，儿童更喜欢口香糖剂型。
两种剂型的蜂胶均能减少菌斑积聚和微生物数量，这表明其可作为不同剂型的抗菌剂使用。
