Khabazian Arezou, Mirhashemi Fatemeh Sadat, Sadeghi Faezeh
Department of Periodontology, Faculty of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
DDS. Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
BMC Oral Health. 2025 Feb 13;25(1):231. doi: 10.1186/s12903-025-05564-8.
The aim of this parallel clinical trial is to investigate the effectiveness of propolis-containing chewing gum and mouthwash in reducing gingival inflammation in patients with gingivitis referred to the Periodontology Department of Yazd Dental School in 2022.
For this purpose, a total of 20 patients were randomly assigned to either the mouthwash group or the chewing gum group. Plaque index (PI), papillary bleeding index (PBI), and gingival index (GI) were recorded before and after one week of using the assigned product, followed by scaling and root planing (SRP). Statistical analysis was performed using Chi-square, T-Test, Mann-Whitney, Paired Samples, and Wilcoxon Signed Ranks tests.
Both groups showed significant reduction in PI (p-value = 0.0001), PBI (p-value = 0.0001), and GI (p-value = 0.003 for chewing gum group and p-value = 0.006 for mouthwash group). There was no significant difference between the two groups in terms of PI (p-value = 0.686), PBI (p-value = 0.737), and GI (p-value = 1.000).
It can be concluded that both propolis-containing chewing gum and mouthwash can effectively reduce dental plaque, papillary bleeding, and gingival inflammation in patients with gingivitis. No significant difference was observed between the two products in terms of effectiveness.
The study was registered at IRCT (IRCT20220420054592N1).It was retrospectively registered on 11/6/2022.
这项平行临床试验的目的是研究含蜂胶口香糖和漱口水对2022年转诊至亚兹德牙科学院牙周病科的牙龈炎患者减轻牙龈炎症的有效性。
为此，总共20名患者被随机分配到漱口水组或口香糖组。在使用指定产品一周前后记录菌斑指数（PI）、龈乳头出血指数（PBI）和牙龈指数（GI），随后进行龈下刮治和根面平整（SRP）。使用卡方检验、T检验、曼-惠特尼检验、配对样本检验和威尔科克森符号秩检验进行统计分析。
两组的PI（p值 = 0.0001）、PBI（p值 = 0.0001）和GI（口香糖组p值 = 0.003，漱口水组p值 = 0.006）均显著降低。两组在PI（p值 = 0.686）、PBI（p值 = 0.737）和GI（p值 = 1.000）方面无显著差异。
可以得出结论，含蜂胶口香糖和漱口水均可有效减少牙龈炎患者的牙菌斑、龈乳头出血和牙龈炎症。两种产品在有效性方面未观察到显著差异。
该研究在伊朗临床试验注册中心（IRCT）注册（IRCT20220420054592N1）。于2022年6月11日进行回顾性注册。
