Bykov V L, Karaev Z O, Velichko E V
Zh Mikrobiol Epidemiol Immunobiol. 1987 Aug(8):13-5.
Changes in the adhesion of Candida cells to the mucous membrane of the oral cavity were studied in vitro in experiments with epithelial cells from 12 normal women at various stages of the menstrual cycle. Fungal cells more actively adhered to the epithelial cells obtained at the follicular phase of the menstrual cycle than to those obtained at its luteal phase. At the follicular phase, both the average level of adhesion and the population of epithelial cells with most pronounced adhesive properties increased. The range of variations in adhesion levels was different in individual subjects and varied from 8% to 37% of the individual mean of the whole cycle. The results of this study indicate the existence of the hormonal control of the adhesion of Candida cells to human epithelial cells.
在体外实验中，研究了念珠菌细胞对12名处于月经周期不同阶段的正常女性口腔黏膜的黏附变化。真菌细胞对在月经周期卵泡期获得的上皮细胞的黏附比黄体期获得的上皮细胞更活跃。在卵泡期，黏附的平均水平和具有最明显黏附特性的上皮细胞数量均增加。个体受试者黏附水平的变化范围不同，从整个周期个体平均值的8%到37%不等。本研究结果表明存在对念珠菌细胞与人上皮细胞黏附的激素调控。
