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估算二手烟和香烟及电加热烟草制品气溶胶的致癌潜能。

Estimating the Carcinogenic Potency of Second-Hand Smoke and Aerosol from Cigarettes and Heated Tobacco Products.

机构信息

Division of Tobacco Policy Research, Center for Cancer Control and Information Services, National Cancer Center, Tokyo 104-0045, Japan.

出版信息

Int J Environ Res Public Health. 2020 Nov 10;17(22):8319. doi: 10.3390/ijerph17228319.

DOI:10.3390/ijerph17228319
PMID:33182793
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7697552/
Abstract

The revised Promotion Act, enforced in April 2020, allows the establishment of dedicated smoking rooms for heated tobacco products (HTPs). Since carcinogenicity assessment is unable to determine the safe level of secondhand smoke, we estimated excess lifetime cancer risk using previously reported risk factors. Assuming that nicotine inhalation is proportional to cancer potency, the lifetime cancer risk for HTP IQOS is expected to be below 10 (1/100,000), which is three orders of magnitude lower than that for cigarettes.

摘要

修订后的《促进法》于 2020 年 4 月生效,允许为加热烟草产品(HTPs)设立专门的吸烟室。由于致癌性评估无法确定二手烟的安全水平,我们使用先前报告的风险因素来估计过量的终生癌症风险。假设尼古丁吸入与癌症效力成正比,HTP IQOS 的终生癌症风险预计低于 10(1/100000),这比香烟低三个数量级。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f249/7697552/2d798df436fc/ijerph-17-08319-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f249/7697552/2d798df436fc/ijerph-17-08319-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f249/7697552/2d798df436fc/ijerph-17-08319-g001.jpg

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2
Air pollutants associated with smoking in indoor/outdoor of waterpipe cafés in Tehran, Iran: Concentrations, affecting factors and health risk assessment.伊朗德黑兰水烟咖啡馆室内/外吸烟相关空气污染物:浓度、影响因素和健康风险评估。
Sci Rep. 2019 Feb 28;9(1):3110. doi: 10.1038/s41598-019-39684-3.
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Lancet. 2018 Nov 10;392(10159):1923-1994. doi: 10.1016/S0140-6736(18)32225-6. Epub 2018 Nov 8.
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Simple Determination of Gaseous and Particulate Compounds Generated from Heated Tobacco Products.加热烟草制品释放的气态和颗粒化合物的简易测定。
Chem Res Toxicol. 2018 Jul 16;31(7):585-593. doi: 10.1021/acs.chemrestox.8b00024. Epub 2018 Jun 19.
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