Aerosp Med Hum Perform. 2020 Oct 1;91(10):826-832. doi: 10.3357/AMHP.5684.2020.
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by multisystem involvement. Clinical management of this condition has unique aeromedical considerations and an impact on subsequent aeromedical disposition. A comprehensive decision matrix would greatly benefit aviation medicine practitioners in the management of aircrew and personnel in flying-related vocations who are diagnosed with SLE. We describe the aeromedical management of a military air traffic controller who was diagnosed with SLE after presenting with cutaneous lupus, nonscarring alopecia, symmetrical small joint polyarthropathy, leukopenia, and presence of SLE-specific antibody. She was treated with hydroxychloroquine and low-dose systemic glucocorticoids, and allowed to return to duties with a proximity restriction and a bar on field deployments and night duties. Several SLE manifestations may have either incapacitating or distracting effects on aircrew and personnel in flying-related vocations. Some medications used in the treatment of SLE may similarly impact on an individuals ability to safely execute flight or air traffic control duties. We propose an aeromedical disposition decision flowchart that would guide aviation medicine practitioners in the management of individuals diagnosed with SLE to ensure optimal and safe performance in their respective occupational settings.
系统性红斑狼疮（SLE）是一种慢性自身免疫性疾病，其特征是多系统受累。这种疾病的临床管理具有独特的航空医学考虑因素，并对随后的航空医学处置产生影响。全面的决策矩阵将极大地有益于航空医学从业者管理被诊断患有 SLE 的机组人员和从事飞行相关职业的人员。我们描述了一名军事空中交通管制员的航空医学管理，该人员在出现皮肤狼疮、非瘢痕性脱发、对称性小关节多关节炎、白细胞减少症和存在 SLE 特异性抗体后被诊断患有 SLE。她接受羟氯喹和低剂量全身糖皮质激素治疗，并允许在近距离限制和禁止野外部署和夜间执勤的情况下返回工作岗位。SLE 的几种表现可能对飞行机组人员和从事飞行相关职业的人员产生致残或分散注意力的影响。SLE 治疗中使用的一些药物也可能同样影响个人安全执行飞行或空中交通管制职责的能力。我们提出了一个航空医学处置决策流程图，该图将指导航空医学从业者管理被诊断患有 SLE 的个人，以确保他们在各自的职业环境中表现最佳和安全。
