Division of Cardiology, Department of Internal Medicine, Chi-Mei Medical Center, Tainan, Taiwan; Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Department of Biotechnology, Southern Taiwan University of Science and Technology, Tainan, Taiwan.
Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Department of Intensive Care Medicine, Chi Mei Medical Center, Tainan, Taiwan.
Am J Med Sci. 2021 Jan;361(1):14-22. doi: 10.1016/j.amjms.2020.10.002. Epub 2020 Oct 6.
Coronavirus Disease 2019 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus. SARS-CoV-2 caused COVID-19 has reached a pandemic level. COVID-19 can significantly affect patients' cardiovascular systems. First, those with COVID-19 and preexisting cardiovascular disease have an increased risk of severe disease and death. Mortality from COVID-19 is strongly associated with cardiovascular disease, diabetes, and hypertension. Second, therapies under investigation for COVID-19 may have cardiovascular side effects of arrhythmia. Third, COVID-19 is associated with multiple direct and indirect cardiovascular complications. Associated with a high inflammatory burden related to cytokine release, COVID-19 can induce vascular inflammation, acute myocardial injury, myocarditis, arrhythmias, venous thromboembolism, metabolic syndrome and Kawasaki disease. Understanding the effects of COVID-19 on the cardiovascular system is essential for providing comprehensive medical care for cardiac and/or COVID-19 patients. We hereby review the literature on COVID-19 regarding cardiovascular virus involvement.
新型冠状病毒病（COVID-19）是由严重急性呼吸系统综合征冠状病毒 2（SARS-CoV-2）病毒引起的传染病。SARS-CoV-2 引起的 COVID-19 已达到大流行水平。COVID-19 可显著影响患者的心血管系统。首先，患有 COVID-19 和既有心血管疾病的患者患重病和死亡的风险增加。COVID-19 的死亡率与心血管疾病、糖尿病和高血压密切相关。其次，正在研究用于治疗 COVID-19 的方法可能具有心律失常的心血管副作用。第三，COVID-19 与多种直接和间接的心血管并发症相关。与与细胞因子释放相关的高炎症负担相关，COVID-19 可引起血管炎症、急性心肌损伤、心肌炎、心律失常、静脉血栓栓塞、代谢综合征和川崎病。了解 COVID-19 对心血管系统的影响对于为心脏和/或 COVID-19 患者提供全面的医疗保健至关重要。在此，我们回顾了 COVID-19 相关心血管病毒感染的文献。
