Zrelovs Nikita, Dislers Andris, Kazaks Andris
Latvian Biomedical Research and Study Centre, Riga, Latvia.
Front Microbiol. 2020 Oct 29;11:579452. doi: 10.3389/fmicb.2020.579452. eCollection 2020.
The first complete genome that was sequenced at the beginning of the sequencing era was that of a phage, since then researchers throughout the world have been steadily describing and publishing genomes from a wide array of phages, uncovering the secrets of the most abundant and diverse biological entities known to man. Currently, we are experiencing an unprecedented rate of novel bacteriophage discovery, which can be seen from the fact that the amount of complete bacteriophage genome entries in public sequence repositories has more than doubled in the past 3 years and is steadily growing without showing any sign of slowing down. The amount of publicly available phage genome-related data can be overwhelming and has been summarized in literature before but quickly becomes out of date. Thus, the aim of this paper is to briefly outline currently available phage diversity data for public acknowledgment that could possibly encourage and stimulate future "depth" studies of particular groups of phages or their gene products.
测序时代开始时测序的首个完整基因组是噬菌体的基因组,从那时起,世界各地的研究人员一直在稳步描述和发表来自各种噬菌体的基因组,揭示了人类已知的最丰富、最多样化的生物实体的秘密。目前,我们正经历着前所未有的新型噬菌体发现速度,从公共序列数据库中完整噬菌体基因组条目的数量在过去3年中增加了一倍多且仍在稳步增长且没有任何放缓迹象这一事实可见一斑。公开可用的噬菌体基因组相关数据量可能非常庞大,之前已有文献进行过总结,但很快就过时了。因此,本文的目的是简要概述当前可用的噬菌体多样性数据,以供公众了解,这可能会鼓励和刺激未来对特定噬菌体群体或其基因产物的“深入”研究。