赤道几内亚马拉博的体外氯喹耐药恶性疟：病例报告。

In vitro chloroquine-resistant falciparum malaria in Malabo, Equatorial Guinea: case reports.

作者信息

Alvar J, Puente S, Blázquez J

机构信息

Centro Nacional de Microbiología, Virología e Immunología Sanitarias, Majadahonda, Madrid, Spain.

出版信息

Diagn Microbiol Infect Dis. 1987 May;7(1):51-3. doi: 10.1016/0732-8893(87)90069-1.

DOI:10.1016/0732-8893(87)90069-1

PMID:3319372

Abstract

For many years the chloroquine-resistant problem in Africa was circumscribed to East Africa, but in the last two years it has been spreading progressively to the West. We report here the two first cases of chloroquine-resistant falciparum malaria imported into Spain from Equatorial Guinea. Both cases show a parasitological grade III resistance in a W.H.O. in vitro macrotest. The clinical recovery with the alternative treatment (Fansidar) was satisfactory.

摘要

多年来，非洲的氯喹耐药问题仅限于东非，但在过去两年中，它已逐渐蔓延到西部。我们在此报告从赤道几内亚输入西班牙的首例两例对氯喹耐药的恶性疟病例。两例病例在世界卫生组织体外宏观试验中均显示出III级寄生虫学耐药性。采用替代疗法（Fansidar）的临床康复情况令人满意。