[一例源自喀麦隆的R3型氯喹耐药疟疾病例]
[A case of chloroquine-resistant malaria of type R3 originating in Cameroon].
作者信息
Alvar J, Barreiros G, Benito A, Ortiz M, Martin-Fontelos P
机构信息
Centro Nacional de Microbiología, Virología e Inmunología Sanitarias, Majadahonda, Madrid, Espagne.
出版信息
Bull Soc Pathol Exot Filiales. 1987;80(3 Pt 2):459-60.
PMID:3319255
Abstract
World areas with chloroquine-resistant falciparum malaria are progressively spreading, in Africa from East to West. We are reporting here a new case of resistance, grade III, from Cameroon, carried out in vitro by the WHO standard macrotest. Resistance is determined by the ability of trophozoites to develop into schizonts when therapeutic doses of chloroquine have been administered.
摘要
对氯喹耐药的恶性疟在世界范围内的流行区域正在逐渐扩大，在非洲已从东部蔓延至西部。我们在此报告来自喀麦隆的一例新的Ⅲ级耐药病例，该病例是通过世界卫生组织标准宏观试验进行体外检测的。耐药性是通过在给予治疗剂量氯喹后滋养体发育为裂殖体的能力来确定的。
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