Gredner Thomas, Niedermaier Tobias, Brenner Hermann, Mons Ute
Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Medical Faculty Heidelberg, University of Heidelberg, Heidelberg, Germany.
Addiction. 2021 Jul;116(7):1677-1688. doi: 10.1111/add.15335. Epub 2021 Jan 12.
Alcohol is a major cancer risk factor and contributes considerably to the cancer burden in Germany. We aimed to provide projections of preventable cancer cases under different price-based alcohol policy scenarios.
A macro-simulation approach was used to estimate numbers and proportions of cancer cases prevented under different price-based alcohol policy scenarios.
Published price elasticities for main alcoholic beverages were applied to the mean daily intake of pure alcohol in the German population calculated from the German Health Interview and Examination Survey for Adults 2008-11 (DEGS1) to obtain hypothetical exposure distributions of alcohol consumption under different scenarios of changing price for alcoholic beverages.
Age, sex and cancer site-specific potential impact fractions were calculated for different scenarios of changing the price of alcohol (single price increases, repeated price increases, volumetric price increase) for each year of a 30-year study period (2020-50).
Over a 30-year horizon, an estimated 4.7% (men = 10.1%, women = 1.4%) of alcohol-related cancer cases could be prevented in Germany, if alcohol intake above risk thresholds were reduced to levels below risk thresholds. Accordingly, the burden of new cancers would be reduced by approximately 244 000 cases (men = 200 000, women = 44 000). Of all price-based alcohol policy scenarios, a 100% price increase on alcoholic beverages was estimated to be most effective with approximately 213 000 (4.1%; men = 167 000; women = 47 000) preventable alcohol-related cancer cases, followed by 5-yearly 25% price increases (2.8%; men = 115 000, women = 29 000) and a volumetric price increase according to the beverage-specific alcohol content (1.9%; men = 72 000, women = 24 000).
Simulations suggest that a substantial number of alcohol-related cancer cases could be avoided in Germany by applying price-based policies to reduce consumption of alcoholic beverages.
酒精是主要的癌症风险因素,在德国对癌症负担有相当大的影响。我们旨在预测不同基于价格的酒精政策情景下可预防的癌症病例数。
采用宏观模拟方法来估计不同基于价格的酒精政策情景下预防的癌症病例数及比例。
将主要酒精饮料已公布的价格弹性应用于根据《2008 - 2011年德国成人健康访谈与检查调查》(DEGS1)计算得出的德国人群纯酒精日均摄入量,以获取在酒精饮料价格变化的不同情景下酒精消费的假设暴露分布。
针对30年研究期(2020 - 2050年)的每一年,计算不同酒精价格变化情景(单次价格上涨、多次价格上涨、按体积计价上涨)下的年龄、性别以及特定癌症部位的潜在影响比例。
在30年的时间跨度内,如果将高于风险阈值的酒精摄入量降低至风险阈值以下,预计德国可预防4.7%(男性为10.1%,女性为1.4%)的酒精相关癌症病例。相应地,新发癌症负担将减少约244000例(男性为200000例,女性为44000例)。在所有基于价格的酒精政策情景中,酒精饮料价格上涨100%估计最为有效,约有213000例(4.1%;男性为167000例;女性为47000例)可预防的酒精相关癌症病例,其次是每5年价格上涨25%(2.8%;男性为115000例,女性为29000例)以及根据饮料特定酒精含量的按体积计价上涨(1.9%;男性为72000例,女性为24000例)。
模拟结果表明,在德国通过应用基于价格的政策来减少酒精饮料消费,可避免大量酒精相关癌症病例的发生。