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儿童双侧特发性眼眶假瘤:病例报告。

Bilateral idiopathic orbital pseudotumour in a child: a case report.

机构信息

The Department of Ophthalmology, The First Affiliated Hospital of Jinan University, No. 613, Huangpu Avenue, Tianhe District of Guangzhou, Guangzhou, Guangdong Province, China.

出版信息

BMC Ophthalmol. 2020 Nov 16;20(1):449. doi: 10.1186/s12886-020-01718-0.

Abstract

BACKGROUND

Idiopathic orbital pseudotumour is rare in children. We report a case of bilateral paediatric idiopathic orbital pseudotumour and review the characteristics of this case.

CASE PRESENTATION

A 14-year-old female patient presented at our Department of Pulmonary and Critical Care Medicine (PCCM) with complaints of recurrent severe cold and cough for 3 weeks, which had been treated with an intravenous antibiotic. Meanwhile, the patient developed swelling of both eyelids during the period of cold and cough, but her symptoms did not improve after the ocular administration of tobramycin dexamethasone eye drops. The patient was referred from the respiratory medicine ward to our department because of gradually worsening ocular pain, visual deterioration, increased intraocular pressure and serious nausea/vomiting within 24 h of hospitalization. The diagnosis of bilateral idiopathic orbital pseudotumour was made ultimately because of the course of the disease, exclusion of diagnoses such as bacterial ocular infection or malignant tumours and subsequent evidence from orbital magnetic resonance imaging (MRI). Favourable progress in the ocular tension and eyelid swelling was achieved through treatment with intravenous dexamethasone. The binocular intraocular pressure gradually declined to approximately 15 mmHg, and there was favourable progression in the patient's vision to 20/40 in both eyes on the ninth day of hospitalization.

CONCLUSIONS

Our patient developed rapidly progressive acute orbital signs and symptoms and anterior inflammation, such as pain, proptosis, limited ductions, periorbital oedema, chemosis, vision loss and high intraocular pressure. This case highlights that idiopathic orbital pseudotumour is an uncommon but important cause of acute orbital syndrome in children.

摘要

背景

特发性眼眶假瘤在儿童中较为罕见。我们报告了一例双侧儿科特发性眼眶假瘤病例,并回顾了该病例的特征。

病例介绍

一名 14 岁女性患者因反复严重感冒和咳嗽 3 周就诊于我院呼吸与危重症医学科(PCCM),此前已接受静脉抗生素治疗。在此期间,患者在感冒和咳嗽期间出现双眼睑肿胀,但在使用妥布霉素地塞米松滴眼液滴眼后症状并未改善。患者因眼部疼痛、视力恶化、眼内压升高和严重恶心/呕吐在住院后 24 小时内逐渐加重,从呼吸科病房转至我科。最终因疾病过程、排除细菌性眼部感染或恶性肿瘤等诊断以及随后的眼眶磁共振成像(MRI)证据,诊断为双侧特发性眼眶假瘤。通过静脉注射地塞米松治疗,患者的眼压和眼睑肿胀得到了良好的改善。双眼眼内压逐渐降至约 15mmHg,住院第 9 天患者的视力在双眼均改善至 20/40。

结论

我们的患者出现了快速进展的急性眼眶症状和前部炎症,如疼痛、眼球突出、运动受限、眶周水肿、球结膜水肿、视力丧失和高眼压。该病例强调了特发性眼眶假瘤是儿童急性眼眶综合征的一个不常见但重要的原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/336f/7670728/d877e489a368/12886_2020_1718_Fig1_HTML.jpg

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