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阪崎肠杆菌中整合型移动元件通过位点特异性重组对[具体物质]的潜在动员作用 。 （注：原文中“Potential Mobilization of by”这里有个关键物质缺失未完整表述）

Potential Mobilization of by an Integrative Mobile Element via Site-Specific Recombination in Cronobacter sakazakii.

作者信息

Yang Jing, Liu Lina, Feng Yu, He Da, Wang Chengcheng, Zong Zhiyong

机构信息

Center of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, China.

Intensive Care Unit, West China Hospital, Sichuan University, Chengdu, China.

出版信息

Antimicrob Agents Chemother. 2021 Jan 20;65(2). doi: 10.1128/AAC.01717-20.

DOI:10.1128/AAC.01717-20
PMID:33199393
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7849017/
Abstract

is a newly identified plasmid-borne colistin resistance gene, but its mobilization mechanism remains unclear. In this study, was found on an IncFIB plasmid carrying virulence genes , /, and in a isolate. By comparison with closely related plasmids, two recombination sites were identified flanking the genetic element containing and an integrase-encoding gene, suggesting that site-specific recombination mediated by an integrase of an integrative mobile element is a potential mechanism for mobilizing .

摘要

是一个新发现的质粒介导的黏菌素抗性基因，但其转移机制仍不清楚。在本研究中，在一株分离菌的携带毒力基因、/和的IncFIB质粒上发现了。通过与密切相关的质粒比较，在包含和一个整合酶编码基因的遗传元件两侧鉴定出两个重组位点，这表明由整合型移动元件的整合酶介导的位点特异性重组是转移的一种潜在机制。

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本文引用的文献

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Identification of novel mobile colistin resistance gene .鉴定新型移动多粘菌素耐药基因。
Emerg Microbes Infect. 2020 Mar 2;9(1):508-516. doi: 10.1080/22221751.2020.1732231. eCollection 2020.
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Towards Understanding MCR-like Colistin Resistance.探索 MCR 样多粘菌素耐药性。
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Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads.单轮循环器：从短读长和长读长测序数据中解析细菌基因组组装结果
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Antibiotic and Desiccation Resistance of and Isolates from Powdered Infant Formula and Processing Environments.来自婴儿配方奶粉粉末及加工环境的[具体名称未给出]分离株的抗生素抗性和干燥抗性
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Insertion Sequence IS26 Reorganizes Plasmids in Clinically Isolated Multidrug-Resistant Bacteria by Replicative Transposition.插入序列IS26通过复制性转座在临床分离的多重耐药细菌中重组质粒。
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Cronobacter, the emergent bacterial pathogen Enterobacter sakazakii comes of age; MLST and whole genome sequence analysis.阪崎肠杆菌，新兴细菌病原体阪崎克罗诺杆菌步入成熟阶段；多位点序列分型及全基因组序列分析
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