1Laboratorio de Microbiología Molecular, Facultad de Medicina, Universidad Nacional de San Agustín, Arequipa, Peru.
2One Health Unit, Zoonotic Disease Research Lab, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru.
Am J Trop Med Hyg. 2020 Nov 16;104(2):700-707. doi: 10.4269/ajtmh.20-0631.
Blastocystis is one of the most common protozoa in the human gut and a zoonotic organism related to unsanitary living conditions. This protozoon shows a broad distribution, unclear symptomatology, and undefined pathogenicity. In Peru, studies report the presence of Blastocystis in many regions, but the highest prevalence levels are reported in Arequipa. The aim of this study was to link Blastocystis infection with social determinants of health. We recruited and surveyed 232 infected and uninfected participants from houses with at least one Blastocystis-infected person. All samples were concentrated by spin concentration method in saline solution, examined by wet mount under light microscopy and confirmed with methylene-stained stool smear. We found a human Blastocystis prevalence of 51.3% in the study sample. We also found statistical associations between Blastocystis infection and peri-urban location in the city as well as the use of alternative non-domiciliary water supplies, suggesting these are risk factors for human Blastocystis infection.
人芽囊原虫是人类肠道中最常见的原生动物之一，也是一种与不卫生生活条件有关的人畜共患病原体。这种原生动物分布广泛，症状不明确，致病性不明确。在秘鲁，有研究报告称在许多地区都存在人芽囊原虫，但在阿雷基帕报告的流行率最高。本研究旨在将人芽囊原虫感染与人的健康社会决定因素联系起来。我们招募并调查了 232 名受感染和未受感染的参与者，他们来自至少有一名人芽囊原虫感染者的家庭。所有样本均采用生理盐水离心浓缩法浓缩，在光镜下用湿片法检查，并经亚甲蓝染色粪便涂片法确认。在研究样本中，我们发现人芽囊原虫的流行率为 51.3%。我们还发现人芽囊原虫感染与城市周边地区以及使用替代非家庭用水供应之间存在统计学关联，表明这些是人类感染人芽囊原虫的危险因素。
