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成年奶牛抗菌药物使用量的量化——第1部分——作为描述抗菌药物使用方法的标准化方案

Antimicrobial use quantification in adult dairy cows - Part 1 - Standardized regimens as a method for describing antimicrobial use.

作者信息

Schrag Nora F D, Apley Michael D, Godden Sandra M, Lubbers Brian V, Singer Randall S

机构信息

College of Veterinary Medicine, Department of Clinical Sciences, Kansas State University, Manhattan, KS, USA.

Department of Veterinary Population Medicine, University of Minnesota, Saint Paul, MN, USA.

出版信息

Zoonoses Public Health. 2020 Nov;67 Suppl 1:51-68. doi: 10.1111/zph.12766.

DOI:10.1111/zph.12766
PMID:33201607
Abstract

This study describes a process to acquire and convert farm treatment records into a standardized regimen format. Multiple sources of on-farm data were utilized to convert the original treatment records to standardized regimens, enabling the generation of objective, granular descriptions of antimicrobial use. These standard regimen descriptions allow antimicrobial use data to be qualitatively stratified by active substance, disease syndrome treated, use category, and route of administration. Quantitative distributions are available for the grams of active substance per administration, the grams of active substance per regimen, the number of administrations, number of days of therapy and the time frame between the first and last administration. Granular quantification by this method informs future research, surveillance and policy.

摘要

本研究描述了一种获取农场治疗记录并将其转换为标准化方案格式的过程。利用农场数据的多个来源将原始治疗记录转换为标准化方案,从而能够生成关于抗菌药物使用的客观、详细描述。这些标准方案描述允许根据活性物质、所治疗的疾病综合征、使用类别和给药途径对抗菌药物使用数据进行定性分层。可获得每次给药的活性物质克数、每个方案的活性物质克数、给药次数、治疗天数以及首次和末次给药之间的时间框架的定量分布。通过这种方法进行的详细量化为未来的研究、监测和政策提供了信息。

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