Department and Division of Practical Cosmetology and Skin Diseases Prophylaxis, Poznan University of Medical Sciences, 33 Mazowiecka Street, 60-623 Poznań, Poland.
Molecules. 2020 Nov 15;25(22):5329. doi: 10.3390/molecules25225329.
Sesquiterpene lactones, coumarins, phytoecdysones and phenolic compounds are characteristic of the species from the subtribe Centaureinae (Asteraceae). Many of the compounds isolated from plants of the Centaureinae subtribe have strong pharmacological properties. It may be suggested that these compounds' chemical structure might be an indicator of these pharmacological properties. The aim of the study was to describe recent studies in the field of phytotherapy, focusing on compounds isolated from chosen plants of Centaureinae and the possibilities of using them to treat antifungal infections, inhibit serotonin and ease symptoms of seborrhea dermatitis and hyperpigmentation. The results of these biological studies have shown that in the future, extracts from the above-mentioned plant material may be used as active substances in new safe and effective drugs.
倍半萜内酯、香豆素、蜕皮甾酮和酚类化合物是 Asteraceae 科 Centaureinae 亚科物种的特征。从 Centaureinae 亚科植物中分离得到的许多化合物具有很强的药理活性。可以推测，这些化合物的化学结构可能是这些药理活性的指标。本研究的目的是描述植物疗法领域的最新研究，重点介绍从选定的 Centaureinae 植物中分离得到的化合物，以及利用它们治疗抗真菌感染、抑制 5-羟色胺和缓解脂溢性皮炎和色素沉着过度症状的可能性。这些生物学研究的结果表明，未来，上述植物材料的提取物可能被用作新型安全有效的药物中的活性物质。
