非编码 RNA 在软体动物中的功能作用。

The functional roles of the non-coding RNAs in molluscs.

机构信息

Guangdong Provincial Key Laboratory of Marine Biotechnology, Institute of Marine Sciences, Shantou University, Shantou 515063, China; Mariculture Research Center for Subtropical Shellfish & Algae of Guangdong Province, Shantou 515063, China; STU-UMT Joint Shellfish Research Laboratory, Shantou University, Shantou 515063, China.

出版信息

Gene. 2021 Feb 5;768:145300. doi: 10.1016/j.gene.2020.145300. Epub 2020 Nov 15.

DOI:10.1016/j.gene.2020.145300

PMID:33207256

Abstract

This review focus on the current knowledge of non-coding RNAs (ncRNAs) in molluscs. In this review, we provide an overview of long ncRNAs (lncRNA), microRNAs (miRNA) and piwi-interacting RNAs (piRNA), followed by evidence for the regulation of ncRNAs in variety of biological process in molluscs, including development, biomineralization and innate immune response. This review advances our understanding on the roles of ncRNAs in molluscs and suggest the future direction to fully understand the epigenetic regulatory network of molluscs.

摘要

这篇综述聚焦于目前关于软体动物中非编码 RNA（ncRNA）的知识。在这篇综述中，我们概述了长 ncRNA（lncRNA）、microRNA（miRNA）和 piwi 相互作用 RNA（piRNA），并提供了证据表明 ncRNA 可以调节软体动物的多种生物学过程，包括发育、生物矿化和先天免疫反应。这篇综述增进了我们对 ncRNA 在软体动物中作用的理解，并为全面了解软体动物的表观遗传调控网络提出了未来的研究方向。