Department of Urology, Xiangya Hospital, Central South University, Changsha 410008, China.
Xiangya International Medical Center, Department of Geriatric Urology, Xiangya Hospital, Central South University, Changsha 410008, China.
Asian J Androl. 2021 May-Jun;23(3):319-324. doi: 10.4103/aja.aja_71_20.
This study aimed to assess the association between psychological disorders and erectile dysfunction (ED) in patients with different degrees of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). This was a retrospective study conducted from June 2017 to October 2019 and included 182 outpatients. Patients were interviewed using the Structured Interview on Erectile Dysfunction (SIEDY) for pathogenic quantification. The National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI) and the International Index of Erectile Function-5 (IIEF-5) were used for the evaluation of CP/CPPS and ED. The Generalized Anxiety Disorder-7 (GAD-7) and Patient Health Questionnaire-9 (PHQ-9) were used to assess anxiety symptoms and depressive symptoms. The number of patients with mild CP/CPPS and mild ED, mild CP/CPPS and moderate-to-severe ED, moderate-to-severe CP/CPPS and mild ED, and moderate-to-severe CP/CPPS and moderate-to-severe ED was 69 (37.9%), 36 (19.8%), 35 (19.2%), and 42 (23.1%), respectively. The corresponding PHQ-9 scores of the four groups were 6.22, 7.19, 10.69, and 7.71, respectively. The corresponding GAD-7 scores of the four groups were 5.26, 6.31, 8.77, and 6.36, respectively. Among patients with moderate-to-severe CP/CPPS, the PHQ-9 and GAD-7 scores of the moderate-to-severe ED group were significantly lower than those of the mild ED group (P = 0.007 and P = 0.010, respectively). The prevalence of ED and premature ejaculation (PE) in patients with moderate-to-severe CP/CPPS was significantly higher than that in patients with mild CP/CPPS (P = 0.001 and P = 0.024, respectively). Our findings proved that the severity of ED was negatively associated with psychological symptoms in outpatients with moderate-to-severe CP/CPPS.
本研究旨在评估不同程度慢性前列腺炎/慢性骨盆疼痛综合征（CP/CPPS）患者中心理障碍与勃起功能障碍（ED）之间的关联。这是一项回顾性研究，于 2017 年 6 月至 2019 年 10 月进行，共纳入 182 名门诊患者。采用勃起功能障碍病因定量结构化访谈（SIEDY）对患者进行访谈。采用国立卫生研究院慢性前列腺炎症状指数（NIH-CPSI）和国际勃起功能指数-5（IIEF-5）评估 CP/CPPS 和 ED。采用广泛性焦虑障碍-7 量表（GAD-7）和患者健康问卷-9（PHQ-9）评估焦虑症状和抑郁症状。轻度 CP/CPPS 和轻度 ED、轻度 CP/CPPS 和中重度 ED、中重度 CP/CPPS 和轻度 ED、中重度 CP/CPPS 和中重度 ED 的患者数量分别为 69 例（37.9%）、36 例（19.8%）、35 例（19.2%）和 42 例（23.1%）。四组的 PHQ-9 评分分别为 6.22、7.19、10.69 和 7.71。四组的 GAD-7 评分分别为 5.26、6.31、8.77 和 6.36。在中重度 CP/CPPS 患者中，中重度 ED 组的 PHQ-9 和 GAD-7 评分明显低于轻度 ED 组（P=0.007 和 P=0.010）。中重度 CP/CPPS 患者的 ED 和早泄（PE）患病率明显高于轻度 CP/CPPS 患者（P=0.001 和 P=0.024）。我们的研究结果证明，在中重度 CP/CPPS 门诊患者中，ED 的严重程度与心理症状呈负相关。
