Kim Jong Duk, Choi Jae Won, Park Hyun Oh, Lee Chung Eun, Jang In Seok, Choi Jun Young, Kang Dong Hoon, Jung Jae Jun, Yang Jun Ho, Moon Sung Ho, Byun Joung Hun, Kim Sung Hwan, Kim Jong Woo
The Department of Cardiothoracic surgery, School of Medicine, Gyeonsang National University, Gyeongsang National University Hospital, Jin-Ju, Republic of South Korea.
The Department of Cardiothoracic surgery, School of Medicine, Gyeonsang National University, Gyeongsang National University Chang-Won Hospital, Chang-Won, Republic of South Korea.
J Thorac Dis. 2020 Oct;12(10):5440-5445. doi: 10.21037/jtd-20-708.
Secondary spontaneous pneumothorax is generally managed by surgery, if pneumothorax was not improved following chest tube insertion or in the event of persistent air leakage lasting more than 5 days. However, if surgery is not an option, chemical pleurodesis with sclerosants can be performed. Several sclerosants have been used in the chemical pleurodesis of secondary spontaneous pneumothorax, However, there is still controversy for what is the ideal sclerosant for Secondary spontaneous pneumothorax. The use of L. for chemical pleurodesis in patients with secondary spontaneous pneumothorax aged >65 years has not been described to date, despite its extensive use. The authors tried to find out the effect of L. for sclerosant for Secondary spontaneous pneumothorax in elder.
This retrospective analysis examined 25 patients (aged >65 years) with secondary spontaneous pneumothorax with persistent air leakage who underwent chemical pleurodesis with Abnova Viscum-F ( L.).
The duration of chest tube drainage was 5.08 days after chemical pleurodesis. Adverse effects related to chemical pleurodesis with Abnova Viscum-F were fever (7/25), pain (4/25), leukocytosis (10/25), and dyspnea with desaturation (7/25); however all the patients recovered without sequela and were subsequently discharged.
The present study demonstrated the successful use of chemical pleurodesis with L. in the management of elderly patients with secondary spontaneous pneumothorax. Because of the high probability of dyspnea with desaturation in the elderly, caution must be exercised.
如果胸腔闭式引流后气胸未改善或持续漏气超过5天，继发性自发性气胸通常采用手术治疗。然而，如果无法进行手术，可以使用硬化剂进行化学性胸膜固定术。几种硬化剂已用于继发性自发性气胸的化学性胸膜固定术，但对于哪种是继发性自发性气胸的理想硬化剂仍存在争议。尽管广泛使用，但迄今为止尚未描述过在年龄>65岁的继发性自发性气胸患者中使用[某种物质，原文未明确写出]进行化学性胸膜固定术的情况。作者试图找出[某种物质，原文未明确写出]作为硬化剂对老年继发性自发性气胸的影响。
这项回顾性分析研究了25例年龄>65岁、持续漏气的继发性自发性气胸患者，他们接受了使用Abnova Viscum - F（[某种物质，原文未明确写出]）的化学性胸膜固定术。
化学性胸膜固定术后胸腔闭式引流的持续时间为5.08天。与使用Abnova Viscum - F进行化学性胸膜固定术相关的不良反应包括发热（7/25）、疼痛（4/25）、白细胞增多（10/25）和伴有血氧饱和度下降的呼吸困难（7/25）；然而所有患者均康复且无后遗症，随后出院。
本研究证明了使用[某种物质，原文未明确写出]进行化学性胸膜固定术成功用于治疗老年继发性自发性气胸患者。由于老年人出现伴有血氧饱和度下降的呼吸困难的可能性较高，必须谨慎操作。
