Davis Joseph T, Wagner Lars M
Department of Radiology, Duke University Medical Center, Durham, NC, USA.
Division of Pediatric Hematology/Oncology, Duke University Medical Center, Durham, NC, USA.
Transl Androl Urol. 2020 Oct;9(5):2348-2357. doi: 10.21037/tau-19-839.
Urologic tumors make up approximately 10% of all pediatric cancers, and include a variety of different histologies and imaging considerations. In this review, we discuss standard radiologic approaches for children with tumors arising in the genitourinary system, and identify important ways in which imaging affects the differential diagnosis, preoperative planning, and staging of these tumors. In addition, we provide an update on strategies to reduce the time of imaging, which may obviate the need for sedation in younger patients. Efforts to reduce a patient's overall radiation exposure and subsequent risk of second malignancy are also detailed, including recent work on surveillance imaging following completion of therapy. Finally, we highlight new techniques such as radiomics that are now being investigated for patients with these malignancies.
泌尿系统肿瘤约占所有儿童癌症的10%,包括多种不同的组织学类型和影像学考量因素。在本综述中,我们讨论了针对泌尿生殖系统肿瘤患儿的标准放射学方法,并确定了影像学在这些肿瘤的鉴别诊断、术前规划和分期中发挥重要作用的方式。此外,我们还介绍了减少成像时间的策略的最新进展,这可能避免对年幼患者进行镇静。我们还详细阐述了降低患者总体辐射暴露及后续发生第二原发性恶性肿瘤风险的措施,包括治疗完成后的监测成像方面的最新研究。最后,我们重点介绍了诸如影像组学等正在针对这些恶性肿瘤患者进行研究的新技术。