Elgin Academy, Elgin, IL 60120, USA.
Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Exp Biol Med (Maywood). 2021 Feb;246(3):293-297. doi: 10.1177/1535370220975118. Epub 2020 Nov 19.
Coronavirus disease 2019 (COVID-19) pandemic has uprooted our lives like never before since its onset in the late December 2019. The world has seen mounting infections and deaths over the past few months despite the unprecedented measures countries are implementing, such as lockdowns, social distancing, mask-wearing, and banning gatherings in large groups. Interestingly, young individuals seem less likely to be impacted by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for COVID-19. While the rate of transmission, symptom presentation, and fatality is lower in children than people from other age groups, they have been disproportionately affected by strict lockdown measures needed to curb viral spread. In this review, we describe the association between patient age and COVID-19, epidemiology of SARS-CoV-2 infection in children, psychological effects associated with lockdowns and school closures, and possible mechanisms underlying lower transmission rate of COVID-19 in children.
自 2019 年 12 月下旬新冠肺炎(COVID-19)疫情爆发以来,它前所未有地打乱了我们的生活。尽管各国采取了前所未有的措施,如封锁、社交距离、戴口罩和禁止大型集会,但在过去的几个月里,感染和死亡人数仍在不断上升。有趣的是,年轻个体似乎不太容易受到严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)的影响,SARS-CoV-2 是导致 COVID-19 的病毒。虽然儿童的传播率、症状表现和病死率低于其他年龄组的人群,但由于需要严格的封锁措施来遏制病毒传播,他们受到的影响不成比例。在这篇综述中,我们描述了患者年龄与 COVID-19 之间的关系、儿童中 SARS-CoV-2 感染的流行病学、与封锁和学校关闭相关的心理影响,以及儿童中 COVID-19 传播率较低的可能机制。