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生命体征:2010-2018 年美国诊断为 HIV 感染者的死亡人数。

Vital Signs: Deaths Among Persons with Diagnosed HIV Infection, United States, 2010-2018.

机构信息

Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, CDC.

出版信息

MMWR Morb Mortal Wkly Rep. 2020 Nov 20;69(46):1717-1724. doi: 10.15585/mmwr.mm6946a1.

Abstract

BACKGROUND

Life expectancy for persons with human immunodeficiency virus (HIV) infection who receive recommended treatment can approach that of the general population, yet HIV remains among the 10 leading causes of death among certain populations. Using surveillance data, CDC assessed progress toward reducing deaths among persons with diagnosed HIV (PWDH).

METHODS

CDC analyzed National HIV Surveillance System data for persons aged ≥13 years to determine age-adjusted death rates per 1,000 PWDH during 2010-2018. Using the International Classification of Diseases, Tenth Revision, deaths with a nonmissing underlying cause were classified as HIV-related or non-HIV-related. Temporal changes in total deaths during 2010-2018 and deaths by cause during 2010-2017 (2018 excluded because of delays in reporting), by demographic characteristics, transmission category, and U.S. Census region of residence at time of death were calculated.

RESULTS

During 2010-2018, rates of death decreased by 36.6% overall (from 19.4 to 12.3 per 1,000 PWDH). During 2010-2017, HIV-related death rates decreased 48.4% (from 9.1 to 4.7), whereas non-HIV-related death rates decreased 8.6% (from 9.3 to 8.5). Rates of HIV-related deaths during 2017 were highest by race/ethnicity among persons of multiple races (7.0) and Black/African American persons (5.6), followed by White persons (3.9) and Hispanic/Latino persons (3.9). The HIV-related death rate was highest in the South (6.0) and lowest in the Northeast (3.2).

CONCLUSION

Early diagnosis, prompt treatment, and maintaining access to high-quality care and treatment have been successful in reducing HIV-related deaths and remain necessary for continuing reductions in HIV-related deaths.

摘要

背景

接受推荐治疗的人类免疫缺陷病毒 (HIV) 感染者的预期寿命可接近普通人群,但 HIV 仍然是某些人群的十大死亡原因之一。利用监测数据,疾病预防控制中心评估了减少已确诊 HIV 感染者 (PWDH) 死亡人数的进展情况。

方法

疾病预防控制中心分析了国家 HIV 监测系统数据,以确定 2010 年至 2018 年期间每 1000 名 PWDH 的年龄调整死亡率。使用国际疾病分类,第十次修订版,对非缺失潜在原因的死亡进行了 HIV 相关或非 HIV 相关的分类。计算了 2010 年至 2018 年期间总死亡人数的时间变化以及 2010 年至 2017 年期间按死因的死亡人数(2018 年因报告延迟而被排除在外),按人口统计学特征、传播类别和死亡时居住的美国人口普查区进行了计算。

结果

2010 年至 2018 年期间,死亡率总体下降了 36.6%(从每 1000 名 PWDH 的 19.4 人降至 12.3 人)。2010 年至 2017 年期间,HIV 相关死亡率下降了 48.4%(从 9.1 人降至 4.7 人),而非 HIV 相关死亡率下降了 8.6%(从 9.3 人降至 8.5 人)。2017 年,多种族人群(7.0)和黑人和非裔美国人(5.6)的 HIV 相关死亡率最高,其次是白人(3.9)和西班牙裔或拉丁裔(3.9)。HIV 相关死亡率在南部最高(6.0),在东北部最低(3.2)。

结论

早期诊断、及时治疗以及维持获得高质量护理和治疗的机会,在减少 HIV 相关死亡方面取得了成功,并且对于继续减少 HIV 相关死亡仍然是必要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5efb/7676640/4b12808266d5/mm6946a1-F1.jpg

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