RNA编辑在人类癌症早期检测中的临床相关性。
Clinical Relevance of RNA Editing to Early Detection of Cancer in Human.
作者信息
Ullah Mujib, Akbar Asma
机构信息
Department of Radiology, School of Medicine, Stanford University, USA.
出版信息
Int J Stem Cell Res Ther. 2020;7(1). doi: 10.23937/2469-570x/1410066. Epub 2020 Mar 14.
Abstract
DNA encodes RNA and is responsible for protein production in cells. RNA editing is the process by which genetic information is altered in the RNA molecule. RNA editing in cancer initiation, progression and development has been well documented and play an important role in tumorigenesis. Studying RNA editing and its application to change genetic information after transcription, RNA-editing technology could be an important innovation in cancer and has the potential for more effective precision treatment. Bioengineering integration approach and artificial intelligence could revolutionize the entire field of RNA editing for early detection of cancer.
摘要
DNA编码RNA，并负责细胞中的蛋白质生产。RNA编辑是RNA分子中遗传信息发生改变的过程。RNA编辑在癌症的起始、进展和发展过程中已有充分记载，并在肿瘤发生中发挥重要作用。研究RNA编辑及其在转录后改变遗传信息的应用，RNA编辑技术可能是癌症领域的一项重要创新，具有实现更有效精准治疗的潜力。生物工程整合方法和人工智能可能会彻底改变RNA编辑领域以实现癌症的早期检测。
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