绿茶补充剂对2型糖尿病患者血清脂联素浓度的影响：一项系统评价和荟萃分析。
Effects of green tea supplementation on serum concentrations of adiponectin in patients with type 2 diabetes mellitus: a systematic review and meta-analysis.
作者信息
Asbaghi Omid, Fouladvand Faezeh, Ashtary-Larky Damoon, Bagheri Reza, Choghakhori Razieh, Wong Alexei, Baker Julien S, Abbasnezhad Amir
机构信息
Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran.
Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
出版信息
Arch Physiol Biochem. 2023 Apr;129(2):536-543. doi: 10.1080/13813455.2020.1846202. Epub 2020 Nov 20.
CONTEXT
A decrease in adiponectin concentration is associated with obesity-related diseases such as insulin resistance, type 2 diabetes mellitus (T2DM), and cardiovascular disease (CVD).
OBJECTIVE
We aimed to evaluate the effects of green tea supplementation on serum concentrations of adiponectin in patients with T2DM.
METHODS
A systematic search was performed on the ISI Web of Science, PubMed, Embase and Scopus to find articles related to the effects of the green tea supplementation on adiponectin concentrations in T2DM patients, up to June 2019. Meta-analyses were performed using both the random and fixed effects model where appropriate.
RESULTS
The initial search yielded 1010 publications. Data were pooled from five trials including 333 patients with T2DM. A meta-analysis of five RCTs demonstrated that green tea supplementation significantly increased adiponectin concentrations compared to control groups.
CONCLUSION
Our meta-analysis revealed that green tea supplementation increased adiponectin concentrations in patients with T2DM.
背景
脂联素浓度降低与肥胖相关疾病有关，如胰岛素抵抗、2型糖尿病（T2DM）和心血管疾病（CVD）。
目的
我们旨在评估补充绿茶对T2DM患者血清脂联素浓度的影响。
方法
在ISI Web of Science、PubMed、Embase和Scopus上进行了系统检索，以查找截至2019年6月与补充绿茶对T2DM患者脂联素浓度影响相关的文章。在适当情况下，使用随机和固定效应模型进行荟萃分析。
结果
初步检索得到1010篇出版物。数据来自五项试验，包括333例T2DM患者。对五项随机对照试验的荟萃分析表明，与对照组相比，补充绿茶显著提高了脂联素浓度。
结论
我们的荟萃分析表明，补充绿茶可提高T2DM患者的脂联素浓度。
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