Department of Sport Physiology, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil 56131-56491, Iran.
Department of Exercise Physiology, University of Isfahan, Isfahan 81746-73441, Iran.
Nutrients. 2021 Nov 5;13(11):3958. doi: 10.3390/nu13113958.
We aimed to investigate the effects of an 8-week total-body resistance exercise (TRX) suspension training intervention combined with taurine supplementation on body composition, blood glucose, and lipid markers in T2D females.
Forty T2D middle-aged females (age: 53 ± 5 years, body mass = 84.3 ± 5.1 kg) were randomly assigned to four groups, TRX suspension training + placebo (TP; = 10), TRX suspension training + taurine supplementation (TT; = 10), taurine supplementation (T; = 10), or control (C; = 10). Body composition (body mass, body mass index (BMI), body fat percentage (BFP)), blood glucose (fasting blood sugar (FBS)), hemoglobin A1c (HbA1c), Insulin, and Insulin resistance (HOMA-IR), and lipid markers (low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglyceride (TG), and total cholesterol (TC)) were evaluated prior to and after interventions.
All three interventions significantly decreased body mass, BMI, and BFP with no changes between them for body mass and BMI; however, BFP changes in the TT group were significantly greater than all other groups. FBS was significantly reduced in TP and TT. Insulin concentrations' decrement were significantly greater in all experimental groups compared to C; however, no between group differences were observed between TT, TP, and T. In regards to HOMA-IR, decreases in TT were significantly greater than all other groups TG, HbA1c, and LDL were reduced following all interventions. HDL values significantly increased only in the TT group, while TC significantly decreased in TP and TT groups. Changes in HbA1c, TG, HDL, and TC were significantly greater in the TT compared to all other groups.
TRX training improved glycemic and lipid profiles, while taurine supplementation alone failed to show hypoglycemic and hypolipidemic properties. Notably, the synergic effects of TRX training and taurine supplementation were shown in HbA1c, HOMA-IR, TG, TC, HDL, and BFP changes. Our outcomes suggest that TRX training + taurine supplementation may be an effective adjuvant therapy in individuals with T2D.
本研究旨在探究 8 周全身抗阻运动（TRX 悬垂训练）联合牛磺酸补充对 T2D 女性的身体成分、血糖和血脂标志物的影响。
40 名 T2D 中年女性（年龄：53 ± 5 岁，体重 = 84.3 ± 5.1kg）被随机分为四组，TRX 悬垂训练+安慰剂（TP；n = 10）、TRX 悬垂训练+牛磺酸补充（TT；n = 10）、牛磺酸补充（T；n = 10）或对照组（C；n = 10）。在干预前后评估身体成分（体重、体重指数（BMI）、体脂百分比（BFP））、血糖（空腹血糖（FBS））、糖化血红蛋白（HbA1c）、胰岛素和胰岛素抵抗（HOMA-IR）以及血脂标志物（低密度脂蛋白（LDL）、高密度脂蛋白（HDL）、甘油三酯（TG）和总胆固醇（TC））。
所有三种干预措施均显著降低了体重、BMI 和 BFP，且体重和 BMI 之间无变化；然而，TT 组的 BFP 变化明显大于其他组。TP 和 TT 组的 FBS 显著降低。与 C 相比，所有实验组的胰岛素浓度均显著降低；然而，在 TT、TP 和 T 之间未观察到组间差异。关于 HOMA-IR，TT 组的降低幅度明显大于其他组。TT 组的 TG、HbA1c 和 LDL 降低，而 HDL 值仅在 TT 组显著升高，TP 和 TT 组的 TC 显著降低。与其他组相比，TT 组的 HbA1c、TG、HDL 和 TC 变化更为显著。
TRX 训练改善了血糖和血脂谱，而单独补充牛磺酸则没有显示出降血糖和降血脂的特性。值得注意的是，TRX 训练和牛磺酸补充的协同作用表现在 HbA1c、HOMA-IR、TG、TC、HDL 和 BFP 的变化上。我们的研究结果表明，TRX 训练+牛磺酸补充可能是 T2D 患者的一种有效的辅助治疗方法。
