Department of Dermatology, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.
Clin Exp Dermatol. 2021 Apr;46(3):430-437. doi: 10.1111/ced.14419. Epub 2020 Nov 20.
Rosacea is a chronic inflammatory condition that affects the skin and the eyes. The pathogenesis of rosacea is complex and includes the interaction between genetic and environmental factors, dysregulation of the innate immune system, neurovascular modifications and the interaction with skin commensals. Clinical manifestations in children include the telangiectatic form, papulopustular rosacea, ocular rosacea, periorificial dermatitis, granulomatous rosacea and idiopathic facial aseptic granuloma. Management is aimed at identifying and avoiding triggers. Topical therapy is used for mild cases with topical antibiotics and anti-inflammatory agents. Oral agents are indicated, in combination with topical therapy, for moderate to severe cases. Prolonged therapy may be required.
酒渣鼻是一种影响皮肤和眼睛的慢性炎症性疾病。酒渣鼻的发病机制复杂，包括遗传和环境因素的相互作用、固有免疫系统失调、神经血管改变以及与皮肤共生菌的相互作用。儿童的临床表现包括毛细血管扩张型、丘疹脓疱型酒渣鼻、眼型酒渣鼻、眶周皮炎、肉芽肿性酒渣鼻和特发性面部无菌性肉芽肿。治疗的目的是确定和避免诱因。对于轻度病例，使用局部抗生素和抗炎药进行局部治疗。对于中重度病例，联合局部治疗，使用口服药物。可能需要长期治疗。
