Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA 02115, USA; Department of Anaesthesia, Harvard Medical School, Boston, MA 02115, USA; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.
Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA 02115, USA; Department of Anaesthesia, Harvard Medical School, Boston, MA 02115, USA.
Clin Immunol. 2021 Jan;222:108635. doi: 10.1016/j.clim.2020.108635. Epub 2020 Nov 17.
A growing literature has shown that volatile anesthetics are promiscuous molecules targeting multiple molecules, some of which are critical for immunological functions. We focused on studies that delineated target molecules of volatile anesthetics on immune cells and summarized the effects of volatile anesthetics on immune functions. We also presented the perspectives of studying volatile anesthetics-mediated immunomodulation.
越来越多的文献表明,挥发性麻醉剂是一种混杂的分子,针对多种分子,其中一些对于免疫功能至关重要。我们专注于研究挥发性麻醉剂在免疫细胞上的靶分子,并总结了挥发性麻醉剂对免疫功能的影响。我们还提出了研究挥发性麻醉剂介导的免疫调节的观点。