Daia Cristina, Scheau Cristian, Neagu Geanina, Andone Ioana, Spanu Aura, Popescu Cristina, Stoica Simona Isabelle, Verenca Madalina Codruta, Onose Gelu
Department of Medical Rehabilitation, "Carol Davila" University of Medicine and Pharmacy, 041914, Bucharest, Romania; Neuromuscular Department, Clinical Emergency Hospital "Bagdasar Arseni", 041914, Bucharest, Romania.
Department of Physiology, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Int J Infect Dis. 2021 Feb;103:420-422. doi: 10.1016/j.ijid.2020.11.146. Epub 2020 Nov 17.
• Three patients with recent sequelae after Corona Virus Disease (COVID)-19 such as fatigue and myalgia of both calves underwent electrophysiological examinations, nerve conduction studies (NCS) and electromyography (EMG). NCS shows, as common elements, the presence of a partial or complete conduction block on several nerves, slightly prolonged latency of the tibial nerve, and rare or absent F-waves, all suggesting a demyelinating polyneuropathy due to SARS−COV-2. The short duration and low amplitude of the motor unit action potential with early full recruitment on interference pattern on EMG, typical for myopathy, suggest a direct action of COVID-19 on muscular fibers, especially in the lower limbs.
• 3例新型冠状病毒肺炎(COVID-19)近期有后遗症(如疲劳和双侧小腿肌痛)的患者接受了电生理检查、神经传导研究(NCS)和肌电图(EMG)检查。神经传导研究显示,作为共同特征,多条神经存在部分或完全性传导阻滞、胫神经潜伏期略有延长以及F波罕见或消失,所有这些均提示由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)导致的脱髓鞘性多发性神经病。肌电图上运动单位动作电位时程短、波幅低,且在干扰相时早期就出现完全募集,这是肌病的典型表现,提示COVID-19对肌纤维有直接作用,尤其是在下肢。